Selected publications

(in Reverse Chronological Order)
2021 ~ present
  • Piao Zhao$, Yi Zhu$, Mirae Kim, Guozhi Zhao, Yonghui Wang, Caralyn P. Collins, Ou Mei, Yuanyuan Zhang, Chongwen Duan, Jiamin Zhong, Hui Zhang, Wulin You, Guowei Shen, Changqi Luo, Xingye Wu, Jingjing Li, Yi Shu, Hue H. Luu, Rex C. Haydon, Michael J. Lee, Lewis L. Shi, Wei Huang, Jiaming Fan, Cheng Sun, Liangyuan Wen*, Guillermo A. Ameer*, Tong-Chuan He*, Russell R. Reid* (2024) Effective bone tissue fabrication using 3D-printed citrate-based nanocomposite scaffolds laden with BMP9-stimulated human urine stem cells. ACS Applied Materials & Interfaces. https://doi.org/10.1021/acsami.4c13246 [in press] ($ equal contribution; * corresponding authors).
  • Yi Zhu, Ou Mei, Hui Zhang, Wulin You, Jiamin Zhong, Caralyn P. Collins, Guowei Shen, Changqi Luo, Xingye Wu, Jingjing Li, Yi Shu, Ya Wen, Hue H. Luu, Lewis L. Shi, Jiaming Fan, Tong-Chuan He, Guillermo A. Ameer, Cheng Sun, Liangyuan Wen*, Russell R. Reid* (2024) Establishment and characterization of a rat model of scalp-cranial composite defect for multilayered tissue engineering. International Journal of Surgery PMID: 39108474; DOI: 10.1097/JS9.0000000000002108 [in press] (* corresponding authors).
  • Sara Romanazzo, Yi Zhu, Rakib Sheikh, Xiaoting Lin, Hongwei Liu, Tong-Chuan He, Iman Roohani* (2024) Highly disordered and resorbable lithiated nanoparticles with osteogenic and angiogenic properties. Journal of Materials Chemistry B 12(38):9575-9591; PMID: 39210776; doi: 10.1039/d4tb00978a [in press]
  • Ethan S. Wong, Daniel A. Hu, Lily Zhang, Rachel Qi, Cindy Xu, Ou Mei, Guowei Shen, Wulin You, Changqi Luo, Tong-Chuan He, Russell R. Reid, Lewis S. Shi, Michael J. Lee*, and Yi Zhu* (2024) Spina Bifida as a Multifactorial Birth Defect: Risk Factors and Genetic Underpinnings. Pediatric Discovery (*corresponding authors) [in press]
  • Mirae Kim, Xinlong Wang, Yiming Li, Zitong Lin, Caralyn P. Collins, Yugang Liu, Yujin Ahn, Hsiu-Ming Tsal, Joseph W. Song, Chongwen Duan, Yi Zhu, Cheng Sun, Tong-Chuan He, Yuan Luo, Russell R. Reid*, Guillermo A. Ameer* (2024) Personalized composite scaffolds 1 for accelerated cell- and growth factor-free craniofacial bone regeneration. Bioactive Materials 41; 427-439; PMID: 39188380; https://doi.org/10.1016/j.bioactmat.2024.07.029
  • Guozhi Zhao, Piao Zhao, Yonghui Wang, Hui Zhang, Yi Zhu, Jiamin Zhong, Wulin You, Guowei Shen, Changqi Luo, Ou Mei, Xingye Wu, Jingjing Li, Yi Shu, Hongwei Wang, William Wagstaff, Hue H. Luu, Yang Bi, Lewis L. Shi, Russell R. Reid, Tong-Chuan He, Li Jiang*, Wei Tang*, Jiaming Fan*, Ziwei Tang* (2024) Glyceraldehyde 3-phosphate dehydrogenase (GAPDH) suppresses adenovirus-induced oxidative stress and enables a superfast production of recombinant adenovirus. Genes & Diseases 11(6):101344; PMID: 39188753; https://doi.org/10.1016/j.gendis.2024.101344 (* corresponding authors)
  • Shuai Tan, Jacobo L Santolaya, Tiffany Freeney Wright, Qi Liu, Teppei Fujikawa, Sensen Chi, Colin P Bergstrom, Adam Lopez, Qing Chen, Goncalo Vale, Jeffrey G McDonald, Andrew Schmidt, Nguyen Vo, Jiwoong Kim, Hamid Baniasadi, Li Li, Gaohui Zhu, Tong-Chuan He, Xiaowei Zhan, Yuuki Obata, Aishun Jin, Da Jia, Joel K Elmquist, Luis Sifuentes-Dominguez, and Ezra Burstein (2024) Interaction between the gut microbiota and colonic enteroendocrine cells regulates host metabolism. Nature Metabolism 6(6):1076-1091; doi: 10.1038/s42255-024-01044-5. PMID: 38777856
  • Han T, Zhu T, Lu Y, Wang Q, Bian H, Chen J, Qiao L, He TC, Q Zheng (2024) Collagen type X expression and chondrocyte hypertrophic differentiation during OA and OS development. Am J Cancer Res. 2024 Apr 15;14(4):1784-1801. doi: 10.62347/JWGW7377. eCollection 2024. PMID: 38726262
  • Gelareh Rezvan, Farivash Gholamirad, Mary K. Walden, Yonghui Wang, Piao Zhao, Tong-Chuan He, and Nader Taheri-Qazvini (2024) Hybrid Functional Membranes through Layer-by-Layer Assembly of Ti3C2Tx MXene and Gelatin-Stabilized Calcium Phosphate Nanospheres. Applied Materials Today Volume 37, April 2024, 102144; https://doi.org/10.1016/j.apmt.2024.102144 [in press]
  • Yannian Gou, Yanran Huang, Wenping Luo, Yanan Li, Piao Zhao, Jiamin Zhong, Xiangyu Dong, Meichun Guo, Aohua Li, Ailing Hao, Guozhi Zhao, Yonghui Wang, Yi Zhu, Hui Zhang, Yunhan Shi, William Wagstaff, Hue H. Luu, Lewis L. Shi, Russell R. Reid, Tong-Chuan He* and Jiaming Fan* (2024) Adipose-derived mesenchymal stem cells (MSCs) are a superior cell source for bone tissue engineering. Bioactive Materials 34:51-63; PMID: 38186960; https://doi.org/10.1016/j.bioactmat.2023.12.003 (*corresponding authors)
  • Xiangyu Dong, Yannian Gou, Meichun Guo, Jiamin Zhong, Aohua Li, Ailing Hao, Wei Zeng, Rex C. Haydon, Hue H. Luu, Russell R. Reid, Tong-Chuan He, Yan Xu and Jiaming Fan* (2024) A simplified noncryogenic strategy to transport mesenchymal stem cells (MSCs): Potential applications in cell therapy and regenerative medicine. Genes & Diseases 11(3): 101073; PMID: https://doi.org/10.1016/j.gendis.2023.07.002
  • Jiamin Zhong, Luyao Tian, Yannian Gou, Piao Zhao, Xiangyu Dong, Meichun Guo, Guozhi Zhao, Aohua Li, Ailing Hao, Tong-Chuan He* and Jiaming Fan* (2023) BMP4 upregulates glycogen synthesis through the SMAD/SLC2A1 (GLUT1) signaling axis in hepatocellular carcinoma (HCC) cells. Cancer & Metabolism 11(1):9 (2023); PMID: 37443106; DOI: 10.1186/s40170-023-00310-6 (*corresponding authors).
  • Michael Yu#, Kevin Qin#, Jiaming Fan, Guozhi Zhao, Piao Zhao, Wei Zeng, Connie Chen, Annie Wang, Yonghui Wang, Jiamin Zhong, Yi Zhu, William Wagstaff, Rex C. Haydon, Hue H. Luu, Sherwin Ho, Michael J. Lee, Jason Strelzow, Russell R. Reid*, and Tong-Chuan He* (2024) The evolving roles of Wnt signaling in stem cell proliferation and differentiation, the development of human diseases, and therapeutic opportunities. Genes & Diseases 11(3): 101026; PMID: ; https://doi.org/10.1016/j.gendis.2023.04.042 (# equal contributions; *corresponding authors)
  • Jiamin Zhong*, Yannian Gou, Piao Zhao, Xiangyu Dong, Meichun Guo, Aohua Li, Ailing Hao, Hue H. Luu, Tong-Chuan He, Russell R. Reid, and Jiaming Fan* (2023) Glycogen storage disease type I (GSDI): Genetic etiology, clinical manifestations, and conventional and gene therapies. Pediatric Discovery 1(2):e3; http://doi.org/10.1002/pdi3.3 (*corresponding authors)
  • Kevin Qin#, Michael Yu#, Jiaming Fan, Hongwei Wang, Piao Zhao, Guozhi Zhao, Wei Zeng, Connie Chen, Yonghui Wang, Annie Wang, Zander Schwartz, Jeffrey Hong, Lily Song, William Wagstaff, Rex C. Haydon, Hue H. Luu, Sherwin H. Ho, Jason Strelzow, Russell R. Reid, Tong-Chuan He*, and Lewis L. Shi* (2024) Canonical and noncanonical Wnt signaling: Multilayered mediators, signaling mechanisms and major signaling crosstalk. Genes & Diseases 11(1):103-134; https://doi.org/10.1016/j.gendis.2023.01.030; PMID: 37588235 (# equal contributions; *corresponding authors)
  • Shaley Albaugh, Ashley Diaz, Esther Wang, Timothy Shen, Lydia Williams, Tong-Chuan He, and Russell R Reid (2023) Systematic review of nonsyndromic craniosynostosis: Genomic alterations and impacted signaling pathways. Plastic and Reconstructive Surgery 10; 1097; PMID: 37070824; DOI: 10.1097/prs.0000000000010522
  • Junyi Liao*, Bowen Chen, Zhenglin Zhu, Chengcheng Du, Shengqiang Gao, Guozhi Zhao, Piao Zhao, Yonghui Wang, Annie Wang, Zander Schwartz, Lily Song, Jeffrey Hong, William Wagstaff, Rex C. Haydon, Hue H. Luu, Jiaming Fan, Russell R. Reid, Tong-Chuan He, Lewis Shi, Ning Hu* and Wei Huang* (2023) Long noncoding RNA (LncRNA) H19: An essential developmental regulator with expanding roles in cancer, stem cell differentiation, and metabolic diseases. Genes & Diseases 10(4):1351-1366; PMID: 37397543; https://doi.org/10.1016/j.gendis.2023.02.008 (*corresponding authors).
  • Xinlong Wang, Vasundhara Agrawal, Cody L. Dunton, Yugang Liu, Ranya K.A. Virk, Priyam A. Patel, Lucas Carter, Emily M. Pujadas, Yue Li, Surbhi Jain, Hao Wang, Na Ni, Nancy Rivera-Bolanos, Jane Frederick, Eric Roth, Reiner Bleher, Chongwen Duan, Panagiotis Ntziachristos, Tong-Chuan He, Russell R. Reid, Bin Jiang, Hariharan Subramanian, Vadim Backman*, and Guillermo A. Ameer* (2023) Biophysical Reprogramming of Chromatin via Contact Guidance-Induced Nuclear Constriction Accelerates Bone Regeneration. Nature Biomedical Engineering 7(11):1514-1529; PMID: 37308586; https://doi.org/10.1038/s41551-023-01053-x (*corresponding authors).
  • Mary Rose Rogers, Wei Zeng, Xian Zhang, Ruidong Li, Qiang Wei, Yuhan Kong, Piao Zhao, Guozhi Zhao, Yonghui Wang, Jiamin Zhong, Yi Zhu, Rex C. Haydon, Hue H. Luu, Russell R. Reid, Daniel A. Peterson, Michael J. Lee, and Tong-Chuan He* (2023) Bone Morphogenic Protein 9 (BMP9)/Growth Differentiation Factor 2 (GDF2) modulates mouse adult hippocampal neurogenesis by regulating the survival of early neural progenitors. Genes & Diseases 10(4):1175-1179; PMID: 37397531; https://doi.org/10.1016/j.gendis.2023.02.018
  • Mengtian Peng, Xiaofei Ma, Yuying Cao, Chunjuan Wang, Qin Tan, Xinyue Chu, Pengfei Zhou, Tiwei Fu, Panpan Liang, Shidian Ran, Tong-Chuan He, Jinhua Wang* and Enyi Huang* (2022) Comparison of the biomechanical differences in the occlusal movement of wild-type and BMP9 knockout mice with apical periodontitis. Frontiers in Bioengineering and Biotechnology. 10:1036061; doi: 10.3389/fbioe.2022.1036061 (*corresponding authors).
  • Linjuan Huang, Jing Zhang, Youling Deng, Hao Wang, Piao Zhao, Guozhi Zhao, Wei Zeng, Yonghui Wang, Connie Chen, William Wagstaff, Rex C. Haydon, Russell R. Reid, Tong-Chuan He, Le Shen, Hue H. Luu, and Ling Zhao* (2023) Niclosamide (NA) overcomes cisplatin resistance in human ovarian cancer. Genes & Diseases 10(4):1687-1701; PMID: 37397523; https://doi.org/10.1016/j.gendis.2022.12.005 (*corresponding author)
  • Jiaming Fan*, Russell R. Reid, and Tong-Chuan He* (2022) Pyrvinium doubles against WNT-driven cancer. Journal of Biological Chemistry 298(10):102479; DOI: https://doi.org/10.1016/j.jbc.2022.102479; PMID: 36096200 (*corresponding authors)
  • Yichun Yu, Jiamin Zhong, Connie Chen, Yannian Gou, Guozhi Zhao, Piao Zhao, Yonghui Wang, Wei Zeng, Annie Wang, William Wagstaff, Rex C. Haydon, Tong-Chuan He, Russell R. Reid, Michael J. Lee, Hue H. Luu*, and Jiaming Fan* (2023) SV40 large T antigen-induced immortalization reprograms mouse cardiomyocyte progenitors with mesenchymal stem cell (MSC) characteristics and osteogenic potential. Genes & Diseases 10(4):1161-1164; PMID: 37397535; https://doi.org/10.1016/j.gendis.2022.10.008 (*corresponding authors)
  • Linghuan Zhang, Wenping Luo, Jiang Liu, Maozhu Xu, Qi Peng, Wenjing Zou, Jingyi You, Yi Shu, Piao Zhao, William Wagstaff, Guozhi Zhao, Kevin Qin, Rex C. Haydon, Hue H. Luu, Russell R. Reid, Yang Bi, Tianyu Zhao, Tong-Chuan He*, and Zhou Fu* (2022) Modeling lung diseases using reversibly immortalized mouse pulmonary alveolar type 2 cells (imPAC2). Cell & Bioscience 12 (1), Article Number: 159; DOI: https://doi.org/10.1186/s13578-022-00894-4; PMID: 36138472 (*corresponding authors)
  • Zander Schwartz, Piao Zhao, Annie Wang, Guozhi Zhao, Wei Zeng, Yonghui Wang, Hue H. Luu, Rex C. Haydon, Tong-Chuan He, Russell R. Reid, and Jason Strelzow* (2023) Engineered nucleus-free mesenchymal stem cells (MSCs) for the targeted delivery of therapeutics to disease site. Genes & Diseases 10(2):310-312; PMID: 37223510; https://doi.org/10.1016/j.gendis.2022.09.001 (*corresponding author).
  • Brandon B. Gardner, Tong-Chuan He, Scott Wu, Wei Liu, Violeta Gutierrez-Sherman, Daniel P. Mass (2022) Growth Factor Expression During Healing In Three Distinct Tendons. Journal of Hand Surgery Global Online. 4(4):214-219; PMID: 35880149; https://doi.org/10.1016/j.jhsg.2022.04.006
  • William Wagstaff, Rimel N. Mwamba, Karina Grullon, Mikhayla Armstrong, Piao Zhao, Bryce Hendren-Santiago, Kevin H. Qin, Alexander J. Li, Daniel A. Hu, Andrew Youssef, Russell R. Reid, Hue H. Luu, Le Shen, Tong-Chuan He* and Rex C. Haydon* (2022) Melanoma --- Molecular genetics, metastasis, targeted therapies, immunotherapies, and therapeutic resistance. Genes & Diseases 9(6): 1608-1623; https://doi.org/10.1016/j.gendis.2022.04.004 (*corresponding authors)
  • Yannian Gou, Yaguang Weng, Qian Chen, Jinghong Wu, Hao Wang, Jiamin Zhong, Yang Bi, Daigui Cao, Piao Zhao, Xiangyu Dong, Meichun Guo, William Wagstaff, Bryce Hendren-Santiago, Connie Chen, Andrew Youssef, Rex C. Haydon, Hue H. Luu, Russell R. Reid, Le Shen, Tong-Chuan He* and Jiaming Fan* (2022) Carboxymethyl chitosan (CMC) prolongs adenovirus-mediated expression of IL-10 and ameliorates hepatic fibrosis in a mouse model. Bioengineering & Translational Medicine 7(3):e10306; PMID: 36176604; https://doi.org/10.1002/btm2.10306 (* corresponding authors).
  • Wenping Luo*, Panpan Liang, Tianyu Zhao, Qianyu Cheng, Huikai Liu, Liwen He, Linghuan Zhang, Bo Huang, Yuxin Zhang, Tong-Chuan He, and Deqin Yang* (2022) Reversely Immortalized Mouse Salivary Gland Cells Presented a Promising Metabolic and Fibrotic Response Upon Bmp9/Gdf2 Stimulation. Cellular & Molecular Biology Letters 27(1):46; PMID: 35690719; PMCID: PMC9188258; https://link.springer.com/article/10.1186/s11658-022-00333-9 (*corresponding authors).
  • Fang He#, Na Ni#, Hao Wang, Zongyue Zeng, Piao Zhao, Deyao Shi, Yinglin Xia, Connie Chen, Daniel A. Hu, Kevin H. Qin, William Wagstaff, David Qin, Bryce Hendren-Santiago, Sherwin H. Ho, Rex C. Haydon, Hue H. Luu, Russell R. Reid, Le Shen, Hua Gan*, Jiaming Fan*, and Tong-Chuan He* (2022) OUHP: An optimized universal hairpin primer system for cost-effective and high throughput RT-qPCR based quantification of microRNA (miRNA) expression. Nucleic Acids Research 50 (4): e22; PMID: 34850128, DOI: 10.1093/nar/gkab1153 (# equal contributions; *corresponding authors).
  • Deyao Shi#, Shidai Mu#, Feifei Pu#, Jianxiang Liu, Binlong Zhong, Binwu Hu, Na Ni, Hao Wang, Hue H Luu, Rex C. Haydon, Le Shen, Zhicai Zhang*, Tong-Chuan He*, and Zengwu Shao* (2022) Integrative analysis of immune related multi-omics profiles identifies distinct prognosis and tumor microenvironment patterns in osteosarcoma. Molecular Oncology. 16 (11):2174-2194. doi: 10.1002/1878-0261.13160. PMID: 34894177 (# equal contributions; *corresponding authors).
  • Feifei Pu, Fengxia Chen, Zhicai Zhang, Deyao Shi, Binlong Zhong, Xiao Lv, Andrew Blake Tucker, Jiaming Fan, Alexander J. Li, Kevin Qin, Daniel Hu, Connie Chen, Hao Wang, Fang He, Na Ni, Linjuan Huang, Qing Liu, William Wagstaff, Hue H. Luu, Rex C. Haydon, Le Shen, Tong-Chuan He, Jianxiang Liu*, Zengwu Shao* (2022) Ferroptosis as a novel form of regulated cell death: Implications in the pathogenesis, oncometabolism and treatment of human cancer. Genes & Diseases 9(2): 347-357; doi.org/10.1016/j.gendis.2020.11.019 (*corresponding authors)
  • Jiamin Zhong#, Hao Wang#, Ke Yang, Huifeng Wang, Chongwen Duan, Na Ni, Liqin An, Yetao Luo, Piao Zhao, Yannian Gou, Shiyan Sheng, Deyao Shi, Connie Chen, William Wagstaff, Bryce Hendren-Santiago, Rex C. Haydon, Hue H. Luu, Russell R. Reid, Sherwin H. Ho, Guillermo A. Ameer, Le Shen, Tong-Chuan He, Jiaming Fan* (2022): Reversibly immortalized keratinocytes (iKera) facilitate re-epithelization and skin wound healing: Potential applications in cell-based skin tissue engineering. Bioactive Materials 9:523-540; PMID: 34820586 PMCID: PMC8581279; doi.org/10.1016/j.bioactmat.2021.07.022 (# equal contributions; * corresponding author).
  • Changchun Niu*, Di Wu, Alexander J. Li, Kevin H. Qin, Daniel A. Hu, Eric J. Wang, Andrew Blake Tucker, Fang He, Linjuan Huang, Hao Wang, Qing Liu, Na Ni, Deyao Shi, Xia Zhao, Yafang Wan, Tian Li, Tong-Chuan He, and Pu Liao* (2021) Identification of a prognostic signature based on copy number variations (CNVs) and CNV-modulated gene expression in acute myeloid leukemia. American Journal of Translational Research 13(12): 13683–13696; PMID: 35035707; PMCID: PMC8748127 (* corresponding authors)
  • Xia Huang, Qiuman Chen, Wenping Luo, Mikhail Pakvasa, Yuxin Zhang, Liwen Zheng, Shuang Li, Zhuohui Yang, Huan Zeng, Fang Liang, Fugui Zhang, Daniel A. Hu, Kevin H. Qin, Eric J. Wang, David S. Qin, Russell R. Reid, Tong-Chuan He, Aravind Athiviraham, Mostafa El Dafrawy, and Hongmei Zhang* (2022) SATB2: A versatile transcriptional regulator of craniofacial and skeleton development, neurogenesis and tumorigenesis, and its applications in regenerative medicine. Genes & Diseases 9(1): 95-107; https://doi.org/10.1016/j.gendis.2020.10.003 (corresponding author)
  • Na Ni#, Fang Deng#, Fang He, Hao Wang, Deyao Shi, Junyi Liao, Yulong Zou, Hongwei Wang, Piao Zhao, Xue Hu, Connie Chen, Daniel A. Hu, Maya Sabharwal, Kevin H. Qin, William Wagstaff, David Qin, Bryce Hendren-Santiago, Rex C. Haydon, Hue H. Luu, Russell R. Reid, Le Shen, Tong-Chuan He*, and Jiaming Fan* (2021) A one-step construction of adenovirus (OSCA) system using the Gibson DNA Assembly technology. Molecular Therapy – Oncolytics. 23; 602-611; DOI: https://doi.org/10.1016/j.omto.2021.11.011 (# equal contributions; * corresponding authors).
  • Linjuan Huang, Ling Zhao, Jing Zhang, Fang He, Hao Wang, Qing Liu, Deyao Shi, Na Ni, William Wagstaff, Connie Chen, Russell R. Reid, Rex C. Haydon, Hue H. Luu, Le Shen, Tong-Chuan He* and Liangdan Tang* (2021) Antiparasitic mebendazole (MBZ) effectively overcomes cisplatin resistance in human ovarian cancer cells by inhibiting multiple cancer-associated signaling pathways. Aging 13(13):17407-17427; PMID: 34232919; DOI: 10.18632/aging.203232 (* Corresponding authors)
  • Mikhail Pakvasa, Andrew B Tucker, Timothy Shen, Tong-Chuan He, Russell R Reid (2021) The Pleiotropic Intricacies of Hedgehog Signaling: From Craniofacial Patterning to Carcinogenesis. FACE 2(3); 260-274; PMID: 35812774; https://doi.org/10.1177/27325016211024326
  • Yukun Mao, Na Ni, Linjuan Huang, Jiaming Fan, Hao Wang, Fang He, Qing Liu, Deyao Shi, Xia Zhao, Kai Fu, Mikhail Pakvasa, William Wagstaff, Andrew Blake Tucker, Connie Chen, Russell R. Reid, Rex C. Haydon, Sherwin H. Ho, Michael J. Lee, Tong-Chuan He, Jian Yang, Le Shen, Lin Cai*, and Hue H. Luu* (2021): Argonaut (AGO) proteins play an essential role in mediating BMP9-induced osteogenic signaling in mesenchymal stem cells (MSCs). Genes & Diseases 8(6):918-930; PMID: 34522718 PMCID: PMC8427325; doi.org/10.1016/j.gendis.2021.04.004 (*corresponding authors)
  • Xia Zhao, Bo Huang, Hao Wang, Na Ni, Fang He, Qing Liu, Deyao Shi, Connie Chen, Piao Zhao, Xi Wang, William Wagstaff, Mikhail Pakvasa, Andrew B. Tucker, Michael J. Lee, Jennifer Moriatis Wolf, Russell R. Reid, Kelly Hynes, Jason Strelzow, Sherwin H. Ho, Tengbo Yu, Jian Yang, Le Shen, Tong-Chuan He*, and Yongtao Zhang* (2021): A functional autophagy pathway is essential for BMP9-induced osteogenic differentiation of mesenchymal stem cells (MSCs). American Journal of Translational Research 13(5):4233-4250; PMID: 34150011; PMCID: PMC8205769 (*corresponding authors)
  • Xia Zhao, Daniel A. Hu, Di Wu, Fang He, Hao Wang, Linjuan Huang, Deyao Shi, Qing Liu, Na Ni, Mikhail Pakvasa, Yongtao, Zhang, Kai Fu, Kevin H. Qin, Alexander J. Li, Ofir Hagag, Eric J. Wang, Maya Sabharwal, William Wagstaff, Russell R. Reid, Michael J. Lee, Jennifer Moriatis Wolf, Mostafa El Dafrawy, Kelly Hynes, Jason Strelzow , Sherwin H. Ho, Tong-Chuan He*, and Aravind Athiviraham* (2021) Applications of Biocompatible Scaffold Materials in Stem Cell-Based Cartilage Tissue Engineering. Frontiers in Bioengineering and Biotechnology Volume 9: Article 603444; doi: 10.3389/fbioe.2021.603444 (*corresponding authors)
  • Xiaoxing Wu, Zhaoxia Li, Hongyu Zhang, Fang He, Min Qiao, Huaxiu Luo, Jing Zhang, Meng Zhang, Yukun Mao, William Wagstaff, Yongtao Zhang, Changchun Niu, Xia Zhao, Hao Wang, Linjuan Huang, Deyao Shi, Qing Liu, Na Ni, Kai Fu, Rex C. Haydon, Russell R. Reid, Hue H. Luu, Tong-Chuan He, Ziwei Wang, Houjie Liang, Bing-Qiang Zhang*, and Ning Wang* (2021): Modeling colorectal tumorigenesis using the organoids derived from conditionally immortalized mouse intestinal crypt cells (ciMICs). Genes & Diseases 8(6):814-826; PMID:34522710, PMCID: PMC8427244; doi: 10.1016/j.gendis.2021.01.004 (*corresponding authors)
  • Wenping Luo, Linghuan Zhang, Bo Huang, Hongmei Zhang, Yan Zhang, Fugui Zhang, Panpan Liang, Qiuman Chen, Qianyu Cheng, Dongmei Tan, Yi Tan, Jinlin Song, Tianyu Zhao, Rex C. Haydon, Russell R. Reid, Hue H Luu, Michael J. Lee, Mostafa El Dafrawy, Ping Ji, Tong-Chuan He* and Liming Gou* (2021) BMP9-initiated osteogenic/odontogenic differentiation of mouse tooth germ mesenchymal cells (TGMCs) requires Wnt/β-catenin signaling activity. Journal of Cellular and Molecular Medicine. 25(5):2666-2678; PMID: 33605035; doi: 10.1111/jcmm.16293. (*corresponding authors)
  • Mikhail Pakvasa, Pranav Haravu, Michael Boachie-Mensah, Alonzo Jones, Elam Coalson, Junyi Liao, Zongyue Zeng, Di Wu, Kevin Qin, Xiaoxing Wu, Huaxiu Luo, Jing Zhang, Meng Zhang, Fang He, Yukun Mao, Yongtao Zhang, Changchun Niu, Meng Wu, Xia Zhao, Hao Wang, Linjuan Huang, Deyao Shi, Qing Liu, Na Ni, Kai Fu, Michael J. Lee, Jennifer Moriatis Wolf, Aravind Athiviraham, Sherwin S. Ho, Tong-Chuan He, Kelly Hynes, Jason Strelzow, Mostafa El Dafrawy, and Russell R. Reid* (2021) Notch signaling: Its essential roles in bone and craniofacial development. Genes & Diseases 8(1):8-24; PMID: 33569510; doi.org/10.1016/j.gendis.2020.04.006 (*corresponding author)
2011 ~ 2020
  • Yongtao Zhang, Di Wu, Xia Zhao, Mikhail Pakvasa, Andrew Blake Tucker, Huaxiu Luo, Kevin H. Qin, Daniel A. Hu, Eric J. Wang, Alexander J. Li, Meng Zhang, Yukun Mao, Maya Sabharwal, Fang He, Changchun Niu, Hao Wang, Linjuan Huang, Deyao Shi, Qing Liu, Na Ni, Kai Fu, Connie Chen, William Wagstaff, Russell R. Reid, Aravind Athiviraham, Sherwin Ho, Michael J. Lee, Kelly Hynes, Jason Strelzow, Tong-Chuan He*, and Mostafa El Dafrawy* (2020): Stem Cell Friendly Scaffold Biomaterials: Applications for Bone Tissue Engineering and Regenerative Medicine. Frontiers in Bioengineering and Biotechnology 8:598607; PMID: 33381499; DOI:10.3389/fbioe.2020.598607 (*corresponding authors)
  • Ruidong Li, Wenwen Zhang, Zhengjian Yan, Wei Liu, Jiaming Fan, Yixiao Feng, Zongyue Zeng, Daigui Cao, William Wagstaff, Rex C. Haydon, Hue H. Luu, Michael J. Lee, Jennifer M. Wolf, Zhong-Liang Deng, Tong-Chuan He, and Yulong Zou* (2020) Long non-coding RNA (LncRNA) HOTAIR regulates BMP9-induced Osteogenic Differentiation by targeting the proliferation of mesenchymal stem cells (MSCs). Aging-US 13(3):4199-4214; PMID: 33461171; doi: 10.18632/aging.202384 (*corresponding author)
  • Ling Zhao, Linjuan Huang, Jing Zhang, Jiaming Fan, Fang He, Xia Zhao, Hao Wang, Qing Liu, Deyao Shi, Na Ni, William Wagstaff, Mikhail Pakvasa, Kai Fu, Andrew B. Tucker, Connie Chen, Russell R. Reid, Rex C. Haydon, Hue H. Luu, Le Shen, Hongbo Qi* and Tong-Chuan He* (2020) The inhibition of BRAF activity sensitizes chemoresistant human ovarian cancer cells to paclitaxel-induced cytotoxicity and tumor growth inhibition. American Journal of Translational Research 15;12(12):8084-8098. eCollection 2020; PMID: 33437383 (*corresponding authors)
  • Fang He, Na Ni, Zongyue Zeng, Di Wu, Yixiao Feng, Alexander J. Li, Benjamin Luu, Alissa F. Li, Kevin Qin, Eric Wang, Xi Wang, Xiaoxing Wu, Huaxiu Luo, Jing Zhang, Meng Zhang, Yukun Mao, Mikhail Pakvasa, William Wagstaff, Yongtao Zhang, Changchun Niu, Hao Wang, Linjuan Huang, Deyao Shi, Qing Liu, Xia Zhao, Kai Fu, Russell R. Reid, Jennifer Moriatis Wolf, Michael J. Lee, Kelly Hynes, Jason Strelzow, Mostafa El Dafrawy, Hua Gan, Tong-Chuan He*, and Jiaming Fan* (2020) FAMSi: A Synthetic Biology Approach to the Fast Assembly of Multiplex siRNAs for Silencing Gene Expression in Mammalian Cells. Molecular Therapy-Nucleic Acids 22:885-899; DOI: https://doi.org/10.1016/j.omtn.2020.10.007 (*corresponding authors)
  • Daigui Cao, Yan Lei, Zhenyu Ye, Ling Zhao, Hao Wang, Jing Zhang, Fang He, Linjuan Huang, Deyao Shi, Qing Liu, Na Ni, Mikhail Pakvasa, William Wagstaff, Xia Zhao, Kai Fu, Andrew B. Tucker, Connie Chen, Russell R. Reid, Rex C. Haydon, Hue H. Luu, Tong-Chuan He*, and Zhan Liao* (2020) Blockade of IGF/IGF-1R signaling axis with soluble IGF-1R mutants suppresses the cell proliferation and tumor growth of human osteosarcoma. American Journal of Cancer Research 10(10):3248-3266; PMID: 33163268; PMCID: PMC7642656; www.ajcr.us/ISSN:2156-6976/ajcr0120348 (*corresponding authors)
  • Xi Wang, Ling Zhao, Xiaoxing Wu, Huaxiu Luo, Di Wu, Meng Zhang, Jing Zhang, Mikhail Pakvasa, William Wagstaff, Fang He, Yukun Mao, Yongtao Zhang, Changchun Niu, Meng Wu, Xia Zhao, Hao Wang, Linjuan Huang, Deyao Shi, Qing Liu, Na Ni, Kai Fu, Kelly Hynes, Jason Strelzow, Mostafa El Dafrawy, Hongbo Qi, Tong-Chuan He, and Zongyue Zeng* (2021) Development of a simplified and inexpensive RNA depletion method for plasmid DNA purification using size selection magnetic beads (SSMBs). Genes & Diseases 8(3):298-306 https://doi.org/10.1016/j.gendis.2020.04.013 (*corresponding author)
  • Robert D Hoffman, Chang-Yu Li, Kai He, Xiao-Xing Wu, Bai-Cheng He, Tong-Chuan He* and Jian-Li Gao* (2020) Chinese Herbal Medicine and Its Regulatory Effects on Tumor Related T Cells. Frontiers in Pharmacology 11:492 DOI: 10.3389/fphar.2020.00492; PMID: 32372963 (*corresponding authors)
  • Bo Zhang, Lijuan Yang, Zongyue Zeng, Yixiao Feng, Xi Wang, Xiaoxing Wu, Huaxiu Luo, Jing Zhang, Meng Zhang, Mikhail Pakvasa, William Wagstaff, Fang He, Yukun Mao, Kevin Qin, Huimin Ding, Yongtao Zhang, Changchun Niu, Meng Wu, Xia Zhao, Hao Wang, Linjuan Huang, Deyao Shi, Qing Liu, Na Ni, Kai Fu, Aravind Athiviraham, Jennifer Moriatis Wolf, Michael J. Lee, Kelly Hynes, Jason Strelzow, Mostafa El Dafrawy, Yayi Xia* and Tong-Chuan He* (2020) Leptin Potentiates BMP9-Induced Osteogenic Differentiation of Mesenchymal Stem Cells (MSCs) Through the Activation of JAK/STAT Signaling. Stem Cells and Development 29(8):498-510; DOI: 10.1089/scd.2019.0292;PMID: 32041483 *corresponding authors)
  • Zongyue Zeng, Bo Huang, Xi Wang, Jiaming Fan, Bo Zhang, Lijuan Yang, Yixiao Feng, Xiaoxing Wu, Huaxiu Luo, Jing Zhang, Meng Zhang, Fang He, Yukun Mao, Mikhail Pakvas, William Wagstaff, Alexander J. Li, Bin Liu, Huiming Ding, Yongtao Zhang, Changchun Niu, Meng Wu, Xia Zhao, Jennifer Moriatis Wolf, Michael J. Lee, Ailong Huang, Hue H. Luu, Rex C. Haydon, and Tong-Chuan He* (2020) A reverse transcriptase-mediated ribosomal RNA depletion (RTR2D) strategy for the cost-effective construction of RNA sequencing libraries. Journal of Advanced Research 24:239-250; doi.org/10.1016/j.jare.2019.12.005; PMID: 32373357 (* corresponding author)
  • Zhicai Zhang, Jianxiang Liu, Zongyue Zeng, Jiaming Fan, Shifeng Huang, Linghuan Zhang, Bo Zhang, Xi Wang, Yixiao Feng, Zhenyu Ye, Ling Zhao, Daigui Cao, Lijuan Yang, Mikhail Pakvasa, Bin Liu, William Wagstaff, Xiaoxing Wu, Huaxiu Luo, Jing Zhang, Meng Zhang, Fang He, Yukun Mao, Huimin Ding, Yongtao Zhang, Changchun Niu, Rex C. Haydon, Hue H. Luu, Michael Lee, Jennifer Moriatis Wolf, Zhengwu Shao* and Tong-Chuan He* (2019) LncRNA Rmst acts as an important mediator of BMP9-induced osteogenic differentiation of mesenchymal stem cells (MSCs) by antagonizing Notch-targeting microRNAs. Aging-US 11(24):12476-12496; PMID: 31825894; doi.org/10.18632/aging.102583; [PDF] (*corresponding authors)
  • Yi Shu, Yi Wang, Wen-Qiong Lv, Dan-Yi Peng, Juan Li, Hang Zhang, Guang-Jie Jiang, Bi-Jie Yang, Shan Liu, Jia Zhang, Yan-Hua Chen, Shi Tang, Ke-Xing Wan, Jun-Tao Yuan, Wei Guo, Guo Fu, Xin-Kun Qi, Zhi-Dai Liu, Hai-Yan Liu, Chao Yang, Ling-Huan Zhang, Fang-Jie Liu, Jie Yu, Peng-Hui Zhang, Bin Qu, Hui Zhao, Tong-Chuan He#, and Lin Zou# (2020) ARRB1-promoted NOTCH1 degradation is mitigated by oncomiR miR-223 in T cell acute lymphoblastic leukemia. Cancer Research PMID: 31822496; DOI: 10.1158/0008-5472.CAN-19-1471 [PDF] (# corresponding authors)
  • Bin Liu*, Wang Xin, Jian-Rong Tan, Rui-Ping Zhu, Ting Li, Dan Wang, Sha-Sha Kan, Ding-Kui Xiong, Huan-Huan Li, William Wagstaff, Chan Zhou*, Zhi-Jian Wang*, Yao-Guang Zhang, and Tong-Chuan He (2019) Myelin sheath structure and regeneration in peripheral nerve injury repair. Proceedings of the National Academy of Sciences USA 116(44):22347-22352; PMID: 31611410, PMCID: PMC6825268, DOI: 10.1073/pnas.1910292116 [PDF] (*corresponding authors)
  • Elam Coalson, Elliot Bishop, Wei Liu, Yixiao Feng, Mia Spezia, Bo Liu, Yi Shen, Di Wu, Scott Du, Alexander J. Li, , Zhenyu Ye, Ling Zhao, Daigui Cao, Alissa Li, Ofir Hagag, Alison Deng, Winny Liu, Mingyang Li, Rex C. Haydon, Lewis Shi, Aravind Athiviraham, Michael J. Lee, Jennifer Moriatis Wolf, Guillermo A. Ameer, Tong-Chuan He, and Russell R. Reid: (2019) Stem Cell Therapy for Chronic Skin Wounds in the Era of Personalized Medicine: from Bench to Bedside. Genes & Diseases 6(4):342-358; PMID: 31832514 PMCID: PMC6888708; https://doi.org/10.1016/j.gendis.2019.09.008
  • Hao Wang, Youde Cao, Liqing Shu, Ying Zhu, Qi Peng, Jinghong Wu, Yetao Luo, Guowei Zuo, Jinyong Luo, Lan Zhou1, Qiong Shi, Yaguang Weng, Ailong Huang, Tong-Chuan He, and Jiaming Fan* (2020) Long noncoding RNA (lncRNA) H19 induces hepatic steatosis through activating MLXIPL and mTORC1 networks in hepatocytes. Journal of Cellular and Molecular Medicine 2019 Dec 6[Online ahead of print]; ; PMID: 31809000; doi/full/10.1111/jcmm.14818 (*Corresponding author)
  • Wei Liu, Zhongliang Deng, Zongyue Zeng, Jiaming Fan, Yixiao Feng, Xi Wang, Daigui Cao, Bo Zhang, Lijuan Yang, Bin Liu, Mikhail Pakvasa, William Wagstaff, Xiaoxing Wu, Huaxiu Luo, Jing Zhang, Meng Zhang, Fang He, Yukun Mao, Huiming Ding, Yongtao Zhang, Changchun Niu, Rex C. Haydon, Hue H. Luu, Jennifer Moriatis Wolf, Michael J. Lee, Wei Huang, Tong-Chuan He, and Yulong Zou* (2020) Highly expressed BMP9/GDF2 in postnatal mouse liver and lungs may account for its pleotropic effects on stem cell differentiation, angiogenesis, tumor growth and metabolism. Genes & Diseases 7(2):235-244; PMID: 32215293; https://doi.org/10.1016/j.gendis.2019.08.003
  • Xi Wang, Chengfu Yuan, Bo Huang, Jiaming Fan, Yixiao Feng, Alexander J. Li, Bo Zhang, Yan Lei, Zhenyu Ye, Ling Zhao, Daigui Cao, Lijuan Yang, Di Wu, Xian Chen, Bin Liu, William Wagstaff, Fang He, Xiaoxing Wu, Huaxiu Luo, Jing Zhang, Meng Zhang, Rex C. Haydon, Hue H. Luu, Michael J. Lee, Jennifer Moriatis Wolf, Ailong Huang, Tong-Chuan He* and Zongyue Zeng* (2019) Developing a Versatile Shotgun Cloning Strategy for Single-Vector-Based Multiplex Expression of Short Interfering RNAs (siRNAs) in Mammalian Cells. ACS Synthetic Biology 8(9):2092-2105, doi: 10.1021/acssynbio.9b00203. PMID: 31465214 (*Corresponding authors)
  • Sami Mostafa, Mikhail Pakvasa, Elam Coalson, Allen Zhu, Alex Alverdy, Hector Castillo, Jiaming Fan, Alex Li, Yixiao Feng, Di Wu, Elliott Bishop, Scott Du, Mia Spezia, Alissa Li, Ofir Hagag, Alison Deng, Winny Liu, Mingyang Li, Sherwin S. Ho, Aravind Athiviraham, Michael J. Lee, Jennifer Moriatis Wolf, Guillermo A. Ameer, Hue H. Luu, Rex C. Haydon, Jason Strelzow, Kelly Hynes, Tong-Chuan He*, and Russell R Reid* (2019) The Wonders of BMP9: From mesenchymal stem cell differentiation, angiogenesis, neurogenesis, tumorigenesis, and metabolism to regenerative medicine. Genes & Diseases 6(3):201-223; PMID: 32042861; https://doi.org/10.1016/j.gendis.2019.07.003 [PDF] (*corresponding authors).
  • Jiaming Fan, Yixiao Feng, Ruyi Zhang, Wenwen Zhang, Yi Shu, Zongyue Zeng, Shifeng Huang, Linghuan Zhang, Bo Huang, Di Wu, Bo Zhang, Xi Wang, Yan Lei, Zhenyu Ye, Ling Zhao, Daigui Cao, Lijuan Yang, Xian Chen, Bin Liu, William Wagstaff, Fang He, Xiaoxing Wu, Jing Zhang, Jennifer Moriatis Wolf, Michael J. Lee, Rex C. Haydon, Hue H. Luu, Ailong Huang, Tong-Chuan He* and Shujuan Yan* (2020) A simplified system for the effective expression and delivery of functional mature microRNAs in mammalian cells. Cancer Gene Therapy 27(6):424-437 PMID: 31222181; https://doi.org/10.1038/s41417-019-0113-y [PDF] (*corresponding authors)
  • Bo Huang, Lin-Feng Huang, Ling Zhao, Zongyue Zeng, Xi Wang, Daigui Cao, Lijuan Yang, Zhenyu Ye, Xian Chen, Bin Liu, Tong-Chuan He*, and Xiaozhong Wang* (2019) Microvesicles (MIVs) secreted from adipose-derived stem cells (ADSCs) contain multiple microRNAs and promote the migration and invasion of endothelial cells. Genes & Diseases. 7(2):225-234; PMID: 32215292; doi.org/10.1016/j.gendis.2019.04.005 [PDF] (*corresponding authors)
  • Chen Zhao#, Nader Taheri Qazvini#, Monirosadat Sadati, Zongyue Zeng, Shifeng Huang, Ana Losada De La Lastra, Linghuan Zhang, Yixiao Feng, Wei Liu, Bo Huang, Bo Zhang, Zhengyu Dai, Yi Shen, Xi Wang, Wenping Luo, Bo Liu, Yan Lei, Zhenyu Ye, Ling Zhao, Daigui Cao, Lijuan Yang, Xian Chen, Aravind Athiviraham, Michael J. Lee, Jennifer Moriatis Wolf, Russell R. Reid, Matthew Tirrell, Wei Huang*, Juan J. de Pablo* and Tong-Chuan He* (2019) A pH-triggered, self-assembled, and bioprintable hybrid hydrogel scaffold for mesenchymal stem cell-based bone tissue engineering. ACS Applied Materials & Interfaces. 11(9):8749-8762, doi: 10.1021/acsami.8b19094. PMID: 30734555 [PDF] (#Equal contributions; *Corresponding authors)
  • Linghuan Zhang, Qing Luo, Yi Shu, Zongyue Zeng, Bo Huang, Yixiao Feng, Bo Zhang, Xi Wang, Yan Lei, Zhenyu Ye, Ling Zhao, Daigui Cao, Lijuan Yang, Xian Chen, Bin Liu, William Wagstaff, Russell R. Reid, Hue H. Luu, Rex C. Haydon, Michael J. Lee, Jennifer Moriatis Wolf, Zhou Fu, Tong-Chuan He* and Quan Kang* (2019) Transcriptomic landscape regulated by the 14 types of bone morphogenetic proteins (BMPs) in lineage commitment and differentiation of mesenchymal stem cells (MSCs). Genes & Diseases 6(3):258-275; PMID: 32042865; doi.org/10.1016/j.gendis.2019.03.008 [PDF] (*Corresponding authors).
  • Dongzhe Song, Shifeng Huang, Linghuan Zhang, Wei Liu, Bo Huang, Yixiao Feng, Bo Liu, Tong-Chuan He, Dingming Huang* and Russell R. Reid* (2020) Differential responsiveness to BMP9 between patent and fused suture progenitor cells from craniosynostosis patients. Plastic and Reconstructive Surgery 145 (3):552e-562e; PMID: 32097313 DOI: 10.1097/PRS.0000000000006597 [PDF] (corresponding authors) (selected as the PSRC Best Papers for March 2020)
  • Xia Huang, Feilong Wang, Chen Zhao, Sheng Yang, Qianyu Chen, Yinyin Tang, Fugui Zhang, Yan Zhang, Wenping Luo, Cao Wang, Pengfei Zhou, Stephanie Kim, Guowei Zuo, Ning Hu, Ruidong Li, Tong-Chuan He* and Hongmei Zhang* (2019) Dentinogenesis and tooth-alveolar bone complex defects in BMP9/GDF2 knockout mice. Stem Cells and Development 2019 Feb 28. doi: 10.1089/scd.2018.0230. [Epub ahead of print] PMID: 30816068 [PDF] (*corresponding authors) [cover story]
  • Cody Lee, Elliot S Bishop, Zari Dumanian, Chen Zhao, Dongzhe Song, Fugui Zhang, Yunxiao Zhu, Guillermo A. Ameer, Tong-Chuan He, and Russell R Reid (2019) BMP-9-Stimulated Adipocyte-Derived Mesenchymal Progenitors Entrapped in a Thermoresponsive Nanocomposite Scaffold Facilitate Cranial Defect Repair. Journal of Craniofacial Surgery 30(6): 1915-1919; doi: 10.1097/SCS.0000000000005465; PMID: 30896511
  • Alex Alverdy, Mikhail Pakvasa, Chen Zhao, Sami Mostafa, Wei Liu, Wenping Luo, Jennifer Moriatis Wolf, Guillermo A. Ameer, Tong-Chuan He, Russell R. Reid (2019) Imiquimod acts synergistically with BMP9 via the Notch pathway as an osteoinductive agent in vitro. Plastic and Reconstructive Surgery. 144:1094-1103; doi: 10.1097/PRS.0000000000006159. [Epub ahead of print]; PMID: 31385892 [PDF]
  • Jing Cui #, Wenwen Zhang #*, Enyi Huang, Jia Wang, Junyi Liao, Ruidong Li, Xinyi Yu, Chen Zhao, Zongyue Zeng, Yi Shu, Ruyi Zhang, Shujuan Yan, Jiayan Lei, Chao Yang, Ke Wu, Ying Wu, Shifeng Huang, Xiaojuan Ji, Alexander Li, Cheng Gong, Chengfu Yuan, Linghuan Zhang, Wei Liu, Bo Huang, Yixiao Feng, Liping An, Bo Zhang, Zhengyu Dai, Yi Shen, Wenping Luo, Xi Wang, Ailong Huang, Hue H. Luu, Russell R. Reid, Jennifer Moriatis Wolf, Gopal Thinakaran, Michael J. Lee, and Tong-Chuan He* (2019) BMP9-induced osteoblastic differentiation requires functional Notch signaling in mesenchymal stem cells. Laboratory Investigation 99(1):58-71; DOI: 10.1038/s41374-018-0087-7; PMID: 30353129; [PDF] (# Equal contributions; *corresponding authors)
  • Xin Wang, Xingye Wu, Zhonglin Zhang, Chao Ma, Tingting Wu, Shengli Tang, Zongyue Zeng, Shifeng Huang, Cheng Gong, Chengfu Yuan, Linghuan Zhang, Yixiao Feng, Bo Huang, Wei Liu, Bo Zhang, Yi Shen, Wenping Luo, Xi Wang, Bo Liu, Yan Lei, Zhenyu Ye, Ling Zhao, Daigui Cao, Lijuan Yang, Xian Chen, Rex C. Haydon, Hue H. Luu, Bing Peng, Xubao Liu* and Tong-Chuan He* (2018) Monensin inhibits cell proliferation and tumor growth of chemo-resistant pancreatic cancer cells by targeting the EGFR signaling pathway. Scientific Reports 8(1):17914; PMID: 30559409; DOI:10.1038/s41598-018-36214-5 [PDF] (*corresponding authors)
  • Yi Shu, Ke Wu*, Zongyue Zeng, Shifeng Huang, Xiaojuan Ji, Chengfu Yuan, Linghuan Zhang, Wei Liu, Bo Huang, Yixiao Feng, Bo Zhang, Zhengyu Dai, Yi Shen, Wenping Luo, Xi Wang, Bo Liu, Yan Lei, Zhenyu Ye, Ling Zhao, Daigui Cao, Lijuan Yang, Xian Chen, Hue H. Luu, Russell R. Reid, Jennifer Moriatis Wolf, Michael J. Lee, and Tong-Chuan He* (2018) A simplified system to express circularized inhibitors of microRNA (miRNA) (CimiR) for stable and potent suppression of miRNA functions. Molecular Therapy - Nucleic Acids 13:556-567; PMID: 30414569; doi.org/10.1016/j.omtn.2018.09.025 [PDF] (*Corresponding authors)
  • Chen Zhao, Zongyue Zeng, Nader Taheri Qazvini, Xinyi Yu, Ruyi Zhang, Shujuan Yan, Yi Shu, Yunxiao Zhu, Chongwen Duan, Elliot Bishop, Jiayan Lei, Wenwen Zhang, Chao Yang, Ke Wu, Ying Wu, Liping An, Shifeng Huang, Xiaojuan Ji, Cheng Gong, Chengfu Yuan, Linghuan Zhang, Wei Liu, Bo Huang, Yixiao Feng, Bo Zhang, Zhengyu Dai, Yi Shen, Xi Wang, Wenping Luo, Leonardo Oliveira, Aravind Athiviraham, Michael J. Lee, Jennifer Moriatis Wolf, Guillermo A. Ameer, Russell R. Reid, Tong-Chuan He*, and Wei Huang* (2018) A Thermoresponsive Citrate-Based Graphene Oxide Scaffold Enhances Bone Regeneration from BMP9-Stimulated Adipose-Derived Mesenchymal Stem Cells (MSCs). ACS Biomaterials Science & Engineering. 4(8):2943-2955; PMID: 30906855; DOI: 10.1021/acsbiomaterials.8b00179 [PDF] (*corresponding authors)
  • Xinyi Yu, Yunfeng Xia, Liyi Zeng, Xi Zhang, Liqun Chen, Shujuan Yan, Ruyi Zhang, Chen Zhao, Zongyue Zeng, Yi Shu, Shifeng Huang, Jiayan Lei, Chengfu Yuan, Linghuan Zhang, Yixiao Feng, Wei Liu, Bo Huang, Bo Zhang, Wenping Luo, Xi Wang, Hongmei Zhang, Rex C. Haydon, Hue H. Luu, Tong-Chuan He*, and Hua Gan* (2018) A blockade of PI3Kγ signaling effectively mitigates angiotensin II-induced renal injury and fibrosis in a mouse model. Scientific Reports (2018) 8:10988; PMID: 30030497; DOI:10.1038/s41598-018-29417-3 [PDF] (*corresponding authors)
  • Yixiao Feng, Mia Spezia, Shifeng Huang, Chengfu Yuan, Zongyue Zeng, Linghuan Zhang, Xiaojuan Ji, Wei Liu, Bo Huang, Wenping Luo, Bo Liu, Yan Lei, Scott Du, Akhila Vuppalapati, Hue H. Luu, Rex C. Haydon, Tong-Chuan He, and Guosheng Ren* (2018) Breast cancer development and progression: risk factors, cancer stem cells, signaling pathways, genomics, and molecular pathogenesis. Genes & Diseases 5(2):77-106; PMID: 30258937; https://doi.org/10.1016/j.gendis.2018.05.001 [PDF]
  • Yi Shu, Chao Yang, Xiaojuan Ji, Linghuan Zhang,Yang Bi, Ke Yang, Mengjia Gong, Xing Liu, Qi Guo, Yuxi Su, Xiangyang Qu, Guoxin Nan, Chen Zhao, Zongyue Zeng, Xinyi Yu, Ruyi Zhang, Shujuan Yan, Jiayan Lei, Ke Wu, Ying Wu, Liping An, Shifeng Huang, Cheng Gong, Chengfu Yuan, Wei Liu, Bo Huang, Yixiao Feng, Bo Zhang, Zhengyu Dai, Yi Shen, Wenping Luo, Xi Wang, Rex C Haydon, Hue H. Luu, Russell R. Reid, Jennifer Moriatis Wolf, Michael J. Lee, Tong-Chuan He*, and Yasha Li* (2018) Reversibly immortalized human umbilical cord-derived mesenchymal stem cells (UC-MSCs) are responsive to BMP9-induced osteogenic and adipogenic differentiation. Journal of Cellular Biochemistry 119(11):8872-8886; doi: 10.1002/jcb.27140. PMID: 30076626 [PDF] (*corresponding authors)
  • Shujuan Yan, Ruyi Zhang, Ke Wu, Jing Cui, Shifeng Huang, Xiaojuan Ji, Liping An, Chengfu Yuan, Cheng Gong, Linghuan Zhang, Wei Liu, Yixiao Feng, Bo Zhang, Zhengyu Dai, Yi Shen, Xi Wang, Wenping Luo, Bo Liu, Rex C. Haydon, Michael J. Lee, Russell R. Reid, Jennifer Moriatis Wolf, Qiong Shi, Hue H. Luu, Tong-Chuan He, and Yaguang Weng (2018) Characterization of the essential role of Bone Morphogenetic Protein 9 (BMP9) in osteogenic differentiation of mesenchymal stem cells (MSCs) through RNA interference. Genes & Diseases 5(2):172-184; PMID:30258947; doi.org/10.1016/j.gendis.2018.04.006 [PDF]
  • Xinyi Yu, Feng Liu, Liyi Zeng, Fang He, Ruyi Zhang, Shujuan Yan, Zongyue Zeng, Yi Shu, Chen Zhao, Xingye Wu, Jiayan Lei, Wenwen Zhang, Chao Yang, Ke Wu, Ying Wu, Liping An, Shifeng Huang, Xiaojuan Ji, Cheng Gong, Chengfu Yuan, Linghuan Zhang, Yixiao Feng, Bo Huang, Wei Liu, Bo Zhang, Zhengyu Dai, Xi Wang, Bo Liu, Rex C. Haydon, Hue H. Luu, Hua Gan, Tong-Chuan He* and Liqun Chen* (2018) Niclosamide Exhibits Potent Anticancer Activity and Synergizes with Sorafenib in Human Renal Cell Cancer Cells. Cellular Physiology and Biochemistry 47:957-971; PMID: 29843133; DOI: 10.1159/000490140 [PDF] (*corresponding authors)
  • Xinyi Yu, Liqun Chen, Ke Wu, Shujuan Yan, Ruyi Zhang, Chen Zhao, Zongyue Zeng, Yi Shu, Shifeng Huang, Jiayan Lei, Xiaojuan Ji, Chengfu Yuan, Linghuan Zhang, Yixiao Feng, Wei Liu, Bo Huang, Bo Zhang, Wenping Luo, Xi Wang, Bo Liu, Rex C. Haydon, Hue H. Luu, Tong-Chuan He and Hua Gan (2018) Establishment and functional characterization of the reversibly immortalized mouse glomerular podocytes (imPODs). Genes & Diseases 5(2):137-149; PMID: 30258943; doi.org/10.1016/j.gendis.2018.04.003 [PDF]
  • Simona Morochnik, Yunxiao Zhu, Chongwen Duan, Michelle Cai, Russell R. Reid, Tong-Chuan He, Jason Koh, Igal Szleifer, and Guillermo A. Ameer (2018) A Thermoresponsive, Citrate-based Macromolecule for Bone Regenerative Engineering. Journal of Biomedical Materials Research (Part A) 106(6):1743-1752; doi: 10.1002/jbm.a.36358; PMID: 29396921
  • Zongyue Zeng, Bo Huang, Shifeng Huang, Ruyi Zhang, Shujuan Yan, Xinyi Yu, Yi Shu, Chen Zhao, Jiayan Lei, Wenwen Zhang, Chao Yang, Ke Wu, Ying Wu, Liping An, Xiaojuan Ji, Cheng Gong, Chengfu Yuan, Linghuan Zhang, Wei Liu, Yixiao Feng, Bo Zhang, Zhengyu Dai, Yi Shen, Xi Wang, Wenping Luo, Rex C. Haydon, Hue H. Luu, Lan Zhou, Russell R. Reid, Tong-Chuan He*, and Xingye Wu* (2018) The development of a sensitive fluorescent protein-based transcript reporter for high throughput screening of negative modulators of lncRNAs. Genes & Diseases 5(1):62-74; PMID: 30159383; https://doi.org/10.1016/j.gendis.2018.02.001 [PDF] (*corresponding authors)
  • Xue Hu, Li Li, Xinyi Yu, Ruyi Zhang, Shujuan Yan, Zongyue Zeng, Yi Shu, Chen Zhao, Xingye Wu, Jiayan Lei, Yasha Li, Wenwen Zhang, Chao Yang, Ke Wu, Ying Wu, Liping An, Shifeng Huang, Xiaojuan Ji, Cheng Gong, Chengfu Yuan, Linghuan Zhang, Wei Liu, Bo Huang, Yixiao Feng, Bo Zhang, Rex C. Haydon, Hue H. Luu, Russell R. Reid, Michael J. Lee, Jennifer Moriatis Wolf, Zebo Yu* and Tong-Chuan He* (2017) CRISPR/Cas9-mediated reversibly immortalized mouse bone marrow stromal stem cells (BMSCs) retain multipotent features of mesenchymal stem cells (MSCs). Oncotarget 8(67):111847-111865; PMID:29340096; doi.org/10.18632/oncotarget.22915 [PDF] (* corresponding authors)
  • Elliot S. Bishop, Sami Mostafa, Mikhail Pakvasa, Hue H. Luu, Michael J. Lee, Jennifer Moriatis Wolf, Guillermo A. Ameer, Tong-Chuan He, Russell R. Reid (2017) 3-D bioprinting technologies in tissue engineering and regenerative medicine: Current and future trends. Genes & Diseases. 4;185-195; PMID: 29911158 [PDF] https://doi.org/10.1016/j.gendis.2017.10.002
  • Sarah M. Lyon, Anoop Mayampurath, Dongzhe Song, Jixing Ye, Michael Januszyk, M. Rose Rogers, Ashley Ralston, Tong-Chuan He, and Russell R. Reid (2018) Whole-proteome analysis of human craniosynostotic tissue suggests a link between inflammatory signaling and osteoclast activation in human cranial suture patency. Plastic and Reconstructive Surgery 141(2):250e-260e; doi: 10.1097/PRS.0000000000004025; PMID: 29369995 [PDF]
  • Chen Zhao, Wei Jiang, Nian Zhou, Junyi Liao, Mingming Yang, Ning Hu, Xi Liang, Wei Xu, Hong Chen, Wei Liu, Lewis L. Shi, Leonardo Oliveira, Jennifer Moriatis Wolf, Sherwin Ho, Aravind Athiviraham, H.M. Tsai, Tong-Chuan He, and Wei Huang (2017) Sox9 augments BMP2-induced chondrogenic differentiation by downregulating Smad7 in mesenchymal stem cells (MSCs). Genes & Diseases. 4;229-239, PMID: 29503843 [PDF] https://doi.org/10.1016/j.gendis.2017.10.004
  • Mikhail Pakvasa, Alex Alverdy, Sami Mostafa, Eric Wang, Lucy Fu, Alexander Li, Leonardo Oliveira, Aravind Athiviraham, Michael J. Lee, Jennifer Moriatis Wolf, Tong-Chuan He, Guillermo A. Ameer, and Russell R. Reid (2017) Neural EGF-Like Protein 1 (NELL-1): Signaling Crosstalk in Mesenchymal Stem Cells and Applications in Regenerative Medicine. Genes & Diseases. 4(3):127-137; PMID: 29276737; https://doi.org/10.1016/j.gendis.2017.07.006 [PDF]
  • Junyi Liao, Xinyi Yu, Xue Hu, Jiaming Fan, Jing Wang, Zhicai Zhang, Chen Zhao, Zongyue Zeng, Yi Shu, Ruyi Zhang, Shujuan Yan, Yasha Li, Wenwen Zhang, Jing Cui, Chao Ma, Li Li, Yichun Yu, Tingting Wu, Xingye Wu, Jiayan Lei, Jia Wang, Chao Yang, Ke Wu, Ying Wu, Jun Tang, Bai-Cheng He, Zhong-Liang Deng, Hue H. Luu, Rex C. Haydon, Russell R. Reid, Michael J. Lee, Jennifer Moriatis Wolf, Wei Huang*, and Tong-Chuan He* (2017) lncRNA H19 mediates BMP9-induced osteogenic differentiation of mesenchymal stem cells (MSCs) through Notch signaling. Oncotarget 8(32):53581-53601; doi: 10.18632/oncotarget.18655, PMID: 28881833 [PDF] (*corresponding authors)
  • Cody S. Lee, Elliot S. Bishop, Ruyi Zhang, Xinyi Yu, Evan M. Farina, Shujuan Yan, Chen Zhao, Zongyue Zeng, Yi Shu, Xingye Wu, Jiayan Lei, Yasha Li, Wenwen Zhang, Chao Yang, Ke Wu, Ying Wu, Sherwin Ho, Aravind Athiviraham, Michael J. Lee, Jennifer Moriatis Wolf, Russell R. Reid* and Tong-Chuan He* (2017) Adenovirus-Mediated Gene Delivery: Potential Applications for Gene and Cell-Based Therapies in the New Era of Personalized Medicine. Genes & Diseases 4(2):43-63; PMID: 28944281; DOI: 10.1016/j.gendis.2017.04.001 [PDF] (*corresponding authors)
  • Yulong Zou#, Nader Taheri Qazvini#, Kylie Zane, Monirosadat Sadati, Qiang Wei, Junyi Liao, Jiaming Fan, Dongzhe Song, Jianxiang Liu, Chao Ma, Xiangyang Qu, Liqun Chen, Xinyi Yu, Zhicai Zhang, Chen Zhao, Zongyue Zeng, Ruyi Zhang, Shujuan Yan, Tingting Wu, Xingye Wu, Yi Shu, Yasha Li, Wenwen Zhang, Russell R. Reid0, Michael J. Lee, Jennifer M. Wolf, Matthew Tirrell, Tong-Chuan He, Juan de Pablo* and Zhong-Liang Deng* (2017) Gelatin-derived graphene-silicate hybrid materials are biocompatible and synergistically promote BMP9-induced osteogenic differentiation of mesenchymal stem cells. ACS Applied Materials and Interfaces. 9(19):15922-15932. doi: 10.1021/acsami.7b00272. PMID: 28406027 [PDF] (# These authors contributed equally to the work; *corresponding authors)
  • Qiang Wei*, Jiaming Fan*, Junyi Liao, Yulong Zou, Dongzhe Song, Jianxiang Liu, Jing Cui, Feng Liu, Chao Ma, Xue Hu, Li Li, Yichun Yu, Xiangyang Qu, Liqun Chen, Xinyi Yu, Zhicai Zhang, Chen Zhao, Zongyue Zeng, Ruyi Zhang, Shujuan Yan, Xingye Wu, Yi Shu, Russell R. Reid, Michael J. Lee, Jennifer M. Wolf, and Tong-Chuan He (2017) Engineering the Rapid Adenovirus Production and Amplification (RAPA) Cell Line to Expedite the Generation of Recombinant Adenoviruses. Cellular Physiology and Biochemistry 41:2383-2398; DOI: 10.1159/000475909 [PDF] (* these authors contributed equally to the reported work)
  • Junyi Liao, Qiang Wei, Jiaming Fan, Yulong Zou, Dongzhe Song, Jianxiang Liu, Feng Liu, Chao Ma, Xue Hu, Li Li, Yichun Yu, Xiangyang Qu, Liqun Chen, Xinyi Yu, Zhicai Zhang, Chen Zhao, Zongyue Zeng, Ruyi Zhang, Shujuan Yan, Tingting Wu, Xingye Wu, Yi Shu, Jiayan Lei, Yasha Li, Wenwen Zhang, Jia Wang, Russell Reid, Michael Lee, Wei Huang, Jennifer Wolf, Tong-Chuan He*, and Jing Wang* (2017) Characterization of retroviral infectivity and superinfection resistance during retrovirus-mediated transduction of mammalian cells. Gene Therapy 24(6):333-341. PMID: 28387759; doi: 10.1038/gt.2017.24 [PDF] (* corresponding authors)
  • Junyi Liao, Qiang Wei, Yulong Zou, Jiaming Fan, Dongzhe Song, Jing Cui, Wenwen Zhang, Yunxiao Zhu, Chao Ma, Xue Hu, Xiangyang Qu, Liqun Chen, Xinyi Yu, Zhicai Zhang, Claire Wang, Chen Zhao, Zongyue Zeng, Ruyi Zhang, Shujuan Yan, Tingting Wu, Xingye Wu, Yi Shu, Jiayan Lei, Yasha Li, Hue H. Luu, Michael J. Lee, Russell R. Reid, Guillermo A. Ameer, Jennifer M. Wolf, Tong-Chuan He* and Wei Huang* (2017) Notch Signaling Augments BMP9-Induced Bone Formation by Promoting the Osteogenesis-Angiogenesis Coupling Process in Mesenchymal Stem Cells (MSCs). Cellular Physiology and Biochemistry 41:1905-1923; PMID: 28384643; DOI:10.1159/000471945 [PDF] (*corresponding authors)
  • Dongzhe Song, Fugui Zhang, Russell R. Reid, Jixing Ye, Qiang Wei, Junyi Liao, Yulong Zou, Jiaming Fan, Chao Ma, Xue Hu, Xiangyang Qu, Liqun Chen, Li Li, Yichun Yu, Xinyi Yu, Zhicai Zhang, Chen Zhao, Zongyue Zeng, Ruyi Zhang, Shujuan Yan, Tingting Wu, Xingye Wu, Yi Shu, Jiayan Lei, Yasha Li, Wenwen Zhang, Jia Wang, Michael J. Lee, Jennifer M. Wolf, Dingming Huang* and Tong-Chuan He* (2017) Bone morphogenetic protein 9 (BMP9) induces osteogenesis and adipogenesis in the reversibly immortalized human cranial suture progenitors (iSuPs) derived from the patent sutures of craniosynostosis patients. Journal of Cellular and Molecular Medicine 21(11):2782-2795; PMID: 28470873; DOI: 10.1111/jcmm.13193 [PDF] (* Corresponding authors)
  • Zari P Dumanian, Viktor Tollemar, Jixing Ye, Minpeng Lu, Yunxiao Zhu, Junyi Liao, Guillermo A. Ameer, Tong-Chuan He, and Russell R. Reid (2017) Repair of Critical Sized Cranial Defects with BMP9-transduced Calvarial Cells Delivered in a Thermoresponsive Scaffold. PLoS ONE 12(3): e0172327. PMID: 28249039, doi:10.1371/journal.pone.0172327 [PDF]
  • Jiaming Fan*, Qiang Wei*, Junyi Liao, Yulong Zou, Dongzhe Song, Dongmei Xiong, Chao Ma, Xue Hu, Xiangyang Qu, Liqun Chen, Li Li, Yichun Yu, Xinyi Yu, Zhicai Zhang, Chen Zhao, Zongyue Zeng, Ruyi Zhang, Shujuan Yan, Tingting Wu, Xingye Wu, Yi Shu, Jiayan Lei, Yasha Li, Wenwen Zhang, Rex C. Haydon, Hue H. Luu, Ailong Huang, Tong-Chuan He#, and Hua Tang# (2017) Noncanonical Wnt signaling plays an important role in modulating canonical Wnt-regulated stemness, proliferation and terminal differentiation of hepatic progenitors. Oncotarget 8(16):27105-27119; doi: 10.18632/oncotarget.15637; PMID: 28404920 [PDF] (* these authors contributed equally to the reported work; # corresponding authors)
  • Jing Wang, Junyi Liao, Fugui Zhang, Dongzhe Song, Minpeng Lu, Jianxiang Liu, Qiang Wei, Shengli Tang, Hao Liu, Jiaming Fan, Yulong Zou, Dan Guo, Jiayi Huang, Feng Liu, Chao Ma, Xue Hu, Li Li, Xiangyang Qu, Liqun Chen, Yaguang Weng, Michael J. Lee, Russell R. Reid, Tong-Chuan He* and Jiye Zhang* (2017) NEL-Like Molecule-1 (Nell1) Is Regulated by Bone Morphogenetic Protein 9 (BMP9) and Potentiates BMP9-Induced Osteogenic Differentiation at the Expense of Adipogenesis in Mesenchymal Stem Cells. Cellular Physiology and Biochemistry 41(2):484-500, PMID: 28214873; DOI: 10.1159/000456885 [PDF] (*Corresponding authors)
  • Fugui Zhang, Yong Li, Hongmei Zhang, Enyi Huang, Lina Gao, Wenping Luo, Qiang Wei, Jiaming Fan, Dongzhe Song, Junyi Liao, Yulong Zou, Feng Liu, Jianxiang Liu, Jiayi Huang, Dan Guo, Chao Ma, Xue Hu, Li Li, Xiangyang Qu, Liqun Chen, Xinyi Yu, Zhicai Zhang, Tingting Wu, Hue H. Luu, Rex C. Haydon, Jinlin Song, Tong-Chuan He*, and Ping Ji* (2017) Anthelmintic Mebendazole Enhances Cisplatin’s Effect on Suppressing Cell Proliferation and Promotes Differentiation of Head and Neck Squamous Cell Carcinoma (HNSCC). Oncotarget 8(8):12968-12982; doi: 10.18632/oncotarget.14673. PMID: 28099902 [PDF] (* Corresponding authors)
  • Minpeng Lu, Junyi Liao, Jing Dong, Jun Wu, Hao Qiu, Xin Zhou, Jidong Li, Dianming Jiang, Tong-Chuan He*, and Zhengxue Quan* (2016) An effective treatment of experimental osteomyelitis using the antimicrobial titanium/silver-containing nHP66 (nano-hydroxyapatite/polyamide-66) nanoscaffold biomaterials. Scientific Reports 6:39174, PMID: 27982110, doi: 10.1038/srep39174, [PDF] (*corresponding authors).
  • Fugui Zhang, Jinglin Song, Hongmei Zhang, Enyi Huang, Dongzhe Song, Viktor Tollemar, Jing Wang, Jinhua Wang, Maryam Mohammed, Qiang Wei, Jiaming Fan, Junyi Liao, Yulong Zou, Feng Liu, Xue Hu, Xiangyang Qu, Liqun Chen, Xinyi Yu, Hue H. Luu, Michael J. Lee, Tong-Chuan He*, and Ping Ji* (2016) Wnt and BMP Signaling Crosstalk in Regulating Dental Stem Cells: Implications in Dental Tissue Engineering. Genes & Diseases. 3(4):263-276, doi.org/10.1016/j.gendis.2016.09.004. PMID: 28491933 [PDF] (*corresponding authors)
  • Jian-Li Gao*, Yan-Mei Shui, Wei Jiang, En-Yi Huang, Qi-Yang Shou, Xin Ji, Bai-Cheng He, Gui-Yuan Lv, and Tong-Chuan He* (2016) Hypoxia Pathway and Hypoxia-mediated Extensive Extramedullary Hematopoiesis are involved in Ursolic Acid’s anti-metastatic effect in 4T1 Tumor Bearing Mice. Oncotarget 7(44):71802-71816, doi: 10.18632/oncotarget.12375, PMID: 27708244 [PDF] (*corresponding authors)
  • Sarah M. Lyon, Anoop Mayampurath, M. Rose Rogers, Donald J. Wolfgeher, Sean M. Fisher, Samuel L. Volchenboum, Tong-Chuan He, and Russell R. Reid (2016) A Method for Whole Protein Isolation from Human Cranial Bone. Analytical Biochemistry 2016 Sep 24. pii: S0003-2697(16)30310-4. doi: 10.1016/j.ab.2016.09.021. PMID: 27677936
  • Youlin Deng, Zhongliang Wang, Fugui Zhang, Min Qiao, Zhengjian Yan, Qiang Wei, Jing Wang, Hao Liu, Jiaming Fan, Yulong Zou, Junyi Liao, Xue Hu, Liqun Chen, Xinyi Yu, Rex C. Haydon, Hue H. Luu, Hongbo Qi, Tong-Chuan He* and Junhui Zhang* (2016) A Blockade of IGF Signaling Sensitizes Human Ovarian Cancer Cells to the Anthelmintic Niclosamide-Induced Anti-Proliferative and Anticancer Activities. Cellular Physiology and Biochemistry 39:871-888, PMID: 27497986 DOI: 10.1159/000447797 [PDF] (*corresponding authors)
  • Qiang Wei, Junyi Liao, Xinyi Yu, Eric J. Wang, Claire Wang, Hue H. Luu, Rex C. Haydon, Michael J. Lee, and Tong-Chuan He* (2016) An NgAgo tool for genome editing: did CRISPR/Cas9 just find a competitor? Genes & Diseases 3(3):169-170 PMID: 28066798, DOI: 10.1016/j.gendis.2016.06.001 [PDF]
  • Shun Lu, Jing Wang, Jixing Ye, Yulong Zou, Yunxiao Zhu, Qiang Wei, Xin Wang, Shengli Tang, Hao Liu, Jiaming Fan, Fugui Zhang, Evan M. Farina, Maryam M. Mohammed, Dongzhe Song, Junyi Liao, Jiayi Huang, Dan Guo, Minpeng Lu, Feng Liu, Jianxiang Liu, Li Li, Chao Ma, Xue Hu, Michael J. Lee, Russell R. Reid, Guillermo A. Ameer, Dongsheng Zhou*, and Tong-Chuan He* (2016) Bone morphogenetic protein 9 (BMP9) induces effective bone formation from reversibly immortalized multipotent adipose-derived (iMAD) mesenchymal stem cells. American Journal of Translational Research 8(9):3710-3730, PMID: 27725853, PMCID: PMC5040671 [PDF] (*corresponding authors)
  • Jixing Ye, Jing Wang, Yunxiao Zhu, Qiang Wei, Xin Wang, Jian Yang, Shengli Tang, Hao Liu, Jiaming Fan, Fugui Zhang, Evan M. Farina, Maryam K. Mohammed, Yulong Zou, Dongzhe Song, Junyi Liao, Jiayi Huang, Dan Guo, Minpeng Lu, Feng Liu, Jianxiang Liu, Li Li, Chao Ma, Xue Hu, Rex C. Haydon, Michael J. Lee, Russell R. Reid, Guillermo A. Ameer, Li Yang*, and Tong-Chuan He* (2016) A thermoresponsive polydiolcitrate-gelatin scaffold and delivery system mediates effective bone formation from BMP9-transduced mesenchymal stem cells. Biomedical Materials 11(2): 025021 PMID: 27097687 (*corresponding authors) [selected as the journal's Highlights of 2016]
  • Maryam K. Mohammed, Connie Shao, Jing Wang, Qiang Wei, Xin Wang, Zachary Collier, Shengli Tang, Hao Liu, Fugui Zhang, Jiayi Huang, Dan Guo, Minpeng Lu, Feng Liu, Jianxiang Liu, Chao Ma, Lewis L. Shi, Aravind Athiviraham, Tong-Chuan He* and Michael J. Lee* (2016) Wnt/β-catenin signaling plays an ever-expanding role in stem cell self-renewal, tumorigenesis and cancer chemoresistance. Genes & Diseases 3 (1): 11-40 PMID: 27077077 [PDF] (* corresponding authors)
  • Jing Wang, Qiang Wei, Xin Wang, Shengli Tang, Hao Liu, Fugui Zhang, Maryam K Mohammed, Jiayi Huang, Dan Guo, Minpeng Lu, Feng Liu, Jianxiang Liu, Chao Ma, Xue Hu, Rex C Haydon, Tong-Chuan He*, and Hue H Luu* (2016) Transition to resistance: An unexpected role of the EMT in cancer chemoresistance. Genes & Diseases 3(1): 3-6 doi:10.1016/j.gendis.2016.01.002[PDF] (*corresponding authors)
  • Sahitya K. Denduluri, Bryan Scott, Joseph D. Lamplot, Liangjun Yin, Zhengjian Yan, Zhongliang Wang, Jixing Ye, Jing Wang, Qiang Wei, Maryam K. Mohammed, Rex C. Haydon, Richard Kang, Tong-Chuan He, Aravind Athiviraham, Sherwin H. Ho*, and Lewis L. Shi* (2016) Immortalized Mouse Achilles Tenocytes Demonstrate Long-Term Proliferative Capacity while Retaining Tenogenic Properties. Tissue Engineering, Part C: Methods. 22(3): 280-289, PMID: 26959762 [PDF] (* corresponding authors)
  • Youlin Deng*, Junhui Zhang*, Zhongliang Wang, Zhengjian Yan, Min Qiao, Jixing Ye, Qiang Wei, Jing Wang, Xin Wang, Lianggong Zhao, Shun Lu, Shengli Tang, Maryam K. Mohammed, Hao Liu, Jiaming Fan, Fugui Zhang, Yulong Zou, Junyi Liao, Hongbo Qi, Rex C. Haydon, Hue H. Luu, Tong-Chuan He#, and Liangdan Tang# (2015) Antibiotic monensin synergizes with EGFR inhibitors and oxaliplatin to suppress the proliferation of human ovarian cancer cells. Scientific Reports 5: 17523. PMID: 26639992 [PDF] (*equal contributions, #corresponding authors)
  • Yasha Li, Eric R. Wagner, Zhengjian Yan, Zhonliang Wang, Gaurav Luther, Wei Jiang, Jixing Ye, Qiang Wei, Jing Wang, Lianggong Zhao, Shun Lu, Xin Wang, Maryam K. Mohammed, Shengli Tang, Hao Liu, Jiaming Fan, Fugui Zhang, Yulong Zou, Dongzhe Song, Junyi Liao, Rex C. Haydon, Hue H. Luu*, and Tong-Chuan He* (2015) The Calcium-Binding Protein S100A6 Accelerates Human Osteosarcoma Growth by Promoting Cell Proliferation and Inhibiting Osteogenic Differentiation. Cellular Physiology and Biochemistry 37(6): 2375-2392; PMID: 26646427 [PDF] (*corresponding authors)
  • Ruifang Li, Zhengjian Yan, Jixing Ye, He Huang, Zhongliang Wang, Qiang Wei, Jing Wang, Lianggong Zhao, Shun Lu, Xin Wang, Shengli Tang, Jiaming Fan, Fugui Zhang, Yulong Zou, Dongzhe Song, Lewis L. Shi, Aravind Athiviraham, Michael J. Lee, Tong-Chuan He*, and Zhonglin Zhang* (2016) The Prodomain-Containing BMP9 Produced from a Stable Line Effectively Regulates the Differentiation of Mesenchymal Stem Cells. International Journal of Medical Sciences 13(1): 8-18; PMID: 26816490 [PDF] (*corresponding authors)
  • Ke Yang, Xin Wang, Hongmei Zhang, Zhongliang Wang, Guoxin Nan, Yasha Li, Fugui Zhang, Maryam K. Mohammed, Rex C. Haydon, Hue H. Luu, Yang Bi* and Tong-Chuan He* (2016) The evolving roles of canonical WNT signaling in stem cells and tumorigenesis: Implications in targeted cancer therapies. Laboratory Investigation 96(2):116-136, PMID: 26618721 [PDF] (*corresponding authors)
  • Jordan D. Green, Viktor Tollemar, Mark Dougherty, Zhengjian Yan, Liangjun Yin, Jixing Ye, Zachary Collier, Maryam K. Mohammed, Rex C. Haydon, Hue H. Luu, Richard Kang, Michael J. Lee, Sherwin H. Ho, Tong-Chuan He, Lewis L. Shi,* and Aravind Athiviraham* (2015) Multifaceted signaling regulators of chondrogenesis: Implications in cartilage regeneration and tissue engineering. Genes & Diseases 2(4):307-327, PMID: 26835506 [PDF] (*corresponding authors)
  • Zhengjian Yan, Liangjun Yin, Zhongliang Wang, Jixing Ye, Zhonglin Zhang, Ruifang Li, Sahitya K. Denduluri, Jing Wang, Qiang Wei, Lianggong Zhao, Shun Lu, Xin Wang, Shengli Tang, Lewis L. Shi, Michael J. Lee, Tong-Chuan He* and Zhong-Liang Deng* (2016) A novel organ culture model of mouse intervertebral disc tissues. Cells Tissues Organs. 201(1):38-50; PMID: 26447649 [PDF] (*corresponding authors)
  • Connie Shao, Christine Shen, Emily Lu, Rex C. Haydon, Hue H. Luu, Aravind Athiviraham, Tong-Chuan He*, and Michael J. Lee* (2015) Damage control: Harnessing prostaglandin E2 as a potential healing factor of tissue injuries. Genes & Diseases 2(4):295-298, PMID: 26819965 (*corresponding authors) doi:10.1016/j.gendis.2015.09.002
  • Maryam K. Mohammed, Connie Shao, Hue H. Luu, and Rex C. Haydon (2015) Opening the LOX to bone metastasis: The role of secreted lysyl oxidase in skeletal recurrence of breast cancers. Genes & Diseases 2 (4): 288-290 (*co-corresponding authors) doi:10.1016/j.gendis.2015.08.004
  • Teven CM, Fisher S, Ameer GA, He TC, Reid RR (2015) Biomimetic approaches to complex craniofacial defects. Ann Maxillofac Surg. 5(1): 4-13. doi: 10.4103/2231-0746.161044. PMID: 26389027
  • Qian Zhang, Jing Wang, Fang Deng, Zhengjian Yan, Yinglin Xia, Zhongliang Wang, Jixing Ye, Youlin Deng. Zhonglin Zhang, Min Qiao, Ruifang Li, Sahitya K. Denduluri, Qiang Wei, Lianggong Zhao, Shun Lu, Xin Wang, Shengli Tang, Hao Liu, Hue H. Luu, Rex C. Haydon, Tong-Chuan He* and Li Jiang* (2015) TqPCR: A Touchdown qPCR Assay with Significantly Improved Detection Sensitivity and Amplification Efficiency of SYBR Green qPCR. PLOS ONE 10(7): e0132666, PMID: 26172450 (*corresponding authors)
  • Zhan Liao, Guoxin Nan, Zhengjian Yan, Liyi Zeng, Youlin Deng, Jixing Ye, Zhonglin Zhang, Min Qiao, Ruifang Li, Sahitya Denduluri, Jing Wang, Qiang Wei, Nisha Geng, Lianggong Zhao, Shun Lu, Xin Wang, Guolin Zhou, Hue H Luu, Rex C Haydon, Tong-Chuan He*, and Zhongliang Wang* (2015) The Anthelmintic Drug Niclosamide Inhibits the Proliferative Activity of Human Osteosarcoma Cells by Targeting Multiple Signal Pathways. Current Cancer Drug Targets 15(8):726-38, PMID: 26118906 (*corresponding authors)
  • Sahitya K. Denduluri, Zhongliang Wang, Zhengjian Yan, Jing Wang, Qiang Wei, Maryam K. Mohammed, Rex C. Haydon, Hue, H. Luu, and Tong-Chuan He (2015) Molecular Pathogenesis and Therapeutic Strategies of Human Osteosarcoma. Journal of Biomedical Research 2015 Aug 30;30. doi: 10.7555/JBR.29.20150075. [Epub ahead of print] PMID: 26496981
  • Jing Wang, Qiang Wei, Jixing Ye, Sahitya K. Denduluri, Xin Wang, Maryam K. Mohammed, Hue H. Luu, Rex C. Haydon, Tong-Chuan He (2015) Insider information: Testing cancer drug sensitivity for personalized therapy. Genes & Diseases. 2(3):219-221, PMID: 26491709
  • Xiang Chen, Jing Cui, Zhengjian Yan, Hongmei Zhang, Xian Chen, Ning Wang, Palak Shah, Fang Deng, Chen Zhao, Nisha Geng, Melissa Li, Sahitya K. Denduluri, Rex C. Haydon, Hue H. Luu, Russell R. Reid, and Tong-Chuan He (2015) Sustained high level transgene expression in mammalian cells mediated by the optimized piggyBac transposon system. Genes & Diseases 2(1): 96-105 PMID: 25815368 http://dx.doi.org/10.1016/j.gendis.2014.12.001
  • Hongmei Zhang, Jinhua Wang, Fang Deng, Enyi Huang, Zhengjian Yan, Zhongliang Wang, Youlin Deng, Qian Zhang, Zhonglin Zhang, Jixing Ye, Min Qiao, Ruifang Li, Jing Wang, Qiang Wei, Guolin Zhou, Hue H. Luu, Rex C. Haydon, Tong-Chuan He* and Feng Deng* (2015) Canonical Wnt signaling acts synergistically on BMP9-induced osteo/odontoblastic differentiation of stem cells of dental apical papilla (SCAPs). Biomaterials 39: 145-154, PMID: 25468367 (*corresponding authors) [PDF]
  • Fang Deng, Xiang Chen, Zhan Liao, Zhengjian Yan, Zhongliang Wang, Youlin Deng, Qian Zhang, Zhonglin Zhang, Jixing Ye, Min Qiao, Ruifang Li, Sahitya Denduluri, Jing Wang, Qiang Wei, Melissa Li, Nisha Geng, Lianggong Zhao, Guolin Zhou, Penghui Zhang, Hue H. Luu, Rex C. Haydon, Russell R. Reid, Tian Yang*, and Tong-Chuan He* (2014) A Simplified and Versatile System for the Simultaneous Expression of Multiple siRNAs in Mammalian Cells Using Gibson DNA Assembly. PLOS ONE 9(11): e113064, PMID: 25398142 (* corresponding authors)
  • Sahitya K. Denduluri, Olumuyiwa Idowu, Zhongliang Wang, Zhan Liao, Zhengjian Yan, Maryam K. Mohammed, Jixing Ye, Qiang Wei, Jing Wang, Lianggong Zhao, Hue H. Luu (2015) Insulin-like growth factor (IGF) signaling in tumorigenesis and the development of cancer drug resistance. Genes & Diseases 2(1): 13-25 http://www.sciencedirect.com/science/article/pii/S2352304214000373
  • Chad M. Teven, Evan M. Farina, Jane Rivas, Russell R. Reid (2014) Fibroblast growth factor (FGF) signaling in development and skeletal diseases. Genes & Diseases 1: 199-213; PMID: 25679016
  • Maureen Beederman, Stephanie H. Kim, M. Rose Rogers, Sarah Lyon, Tong-Chuan He, and Russell R. Reid (2015) OPG Deficiency Results in Disruption of Posterofrontal Suture Closure in Mice: Implications in Nonsyndromic Craniosynostosis. Plastic and Reconstructive Surgery 135(6): 990e–999e; PMID: 26017615; PMCID: PMC4602410; doi: 10.1097/PRS.0000000000001284
  • Alice Jo, Sahitya Denduluri, Bosi Zhang, Zhongliang Wang, Liangjun Yin, Zhengjian Yan, Richard Kang, Lewis L. Shi, James Mok, Michael J. Lee, and Rex C. Haydon (2014) The Versatile Functions of Sox9 in Development, Stem Cells, and Human Diseases. Genes & Diseases. 1: 149-161
  • Zhongliang Wang, Jixing Ye, Youlin Deng, Zhengjian Yan, Sahitya Denduluri, and Tong-Chuan He (2014) Wnt versus Hippo: A balanced act or dynamic duo? Genes & Diseases. 1: 127-128; PMID: 25679015
  • Deana S. Shenaq, Chad M. Teven, Iris A. Seitz, Farbod Rastegar, Matthew R. Greives, Tong-Chuan He, Russell R. Reid (2015) Characterization of reversibly immortalized calvarial mesenchymal progenitor cells. Journal of Craniofacial Surgery 26(4):1207-1213; PMID: 26080159
  • Hongmei Zhang, Zhengjian Yan, Melissa Li, Michael Peabody, and Tong-Chuan He (2014) CRISPR Clear? Dimeric Cas9-Fok1 Nucleases Improve Genome-Editing Specificity. Genes & Diseases. 1: 6-7 PMID: 25374931, PMCID: PMC4217641 [PDF]
  • Richard N. Wang, Jordan Green, Zhongliang Wang, Youlin Deng, Min Qiao, Michael Peabody, Qian Zhang, Jixing Ye, Zhengjian Yan, Sahitya Denduluri, Olumuyiwa Idowu, Melissa Li, Christine Shen, Alan Hu, Rex C. Haydon, Richard Kang, James Mok, Michael J. Lee, Hue L. Luu, and Lewis L. Shi (2014) Bone Morphogenetic Protein (BMP) Signaling in Development and Human Diseases. Genes & Diseases 1: 87-105, PMID: 25401122; PMCID: PMC4232216
  • Maureen Beederman, Evan M. Farina, Russell R. Reid (2014) Molecular Basis of Cranial Suture Biology and Disease: Osteoblastic and Osteoclastic Perspectives. Genes & Diseases 1: 120-125, PMID: 25426492
  • Yang Bi, Yun He, Jiayi Huang, Yuxi Su, Gao-Hui Zhu, Yi Wang, Min Qiao, Bing-Qiang Zhang, Hongyu Zhang, Zhongliang Wang, Wei Liu, Jing Cui, Quan Kang, Zhonglin Zhang, Youlin Deng, Ruifang Li, Qian Zhang, Ke Yang, Hue H. Luu, Rex C. Haydon, Tong-Chuan He*, and Ni Tang* (2014) Functional Characteristics of Reversibly Immortalized Hepatic Progenitor Cells Derived from Mouse Embryonic Liver. Cellular Physiology and Biochemistry 34(4):1318-1338, PMID: 25301359 (*corresponding authors)
  • Joseph D Lamplot*, Michael Angeline*, Jovito Angeles, Maureen Beederman, Eric Wagner, Farbod Rastegar, Bryan Scott, Christian Skjong, Daniel Mass, Richard Kang, Sherwin Ho#, and Lewis L. Shi# (2014) Distinct Effects of Platelet-Rich Plasma and BMP13 on Rotator Cuff Tendon Injury Healing in a Rat Model. American Journal of Sports Medicine 42(12): 2877-2887. PMID: 25193888 (*equal contributions; #Corresponding authors).
  • Joseph D. Lamplot*, Bo Liu*, Liangjun Yin, Wenwen Zhang, Zhongliang Wang, Gaurav Luther, Eric Wagner, Ruidong Li, Guoxin Nan, Wei Shui, Zhengjian Yan, Richard Rames, Fang Deng, Hongmei Zhang, Zhan Liao, Wei Liu, Junhui Zhang, Zhonglin Zhang, Qian Zhang, Jixing Ye, Youlin Deng, Min Qiao, Rex C. Haydon, Hue H Luu, Jovito Angeles, Lewis L. Shi, Tong-Chuan He#, and Sherwin H. Ho# (2015) Reversibly Immortalized Mouse Articular Chondrocytes Acquire Long-Term Proliferative Capability while Retaining Chondrogenic Phenotype. Cell Transplantation 24(6):1053-1066 PMID: 24800751 (*equal contributions; #corresponding authors)
  • Yunyuan Zhang, Xian Chen, Min Qiao, Bing-Qiang Zhang, Ning Wang, Zhonglin Zhang, Zhan Liao, Liyi Zeng, Youlin Deng, Fang Deng, Junhui Zhang, Liangjun Yin, Wei Liu, Qian Zhang, Zhengjian Yan, Jixing Ye, Zhongliang Wang, Lan Zhou, Hue H. Luu, Rex C. Haydon, Tong-Chuan He* and Hongyu Zhang* (2014) Bone morphogenetic protein 2 inhibits the proliferation and growth of human colorectal cancer cells. Oncology Reports 32(3):1013-1020, PMID: 24993644 (*corresponding authors)
  • Ning Wang#, Wenwen Zhang#, Jing Cui, Hongmei Zhang, Xiang Chen, Ruidong Li, Ningning Wu, Xian Chen, Sheng Wen, Junhui Zhang, Liangjun Yin, Fang Deng, Zhan Liao, Zhonglin Zhang, Qian Zhang, Zhengjian Yan,Wei Liu, Jixing Ye, Youlin Deng, Zhongliang Wang, Min Qiao, Hue H. Luu, Rex C. Haydon, Lewis L. Shi, Houjie Liang*, and Tong-Chuan He* (2014) The piggyBac Transposon-Mediated Expression of SV40 T Antigen Efficiently Immortalizes Mouse Embryonic Fibroblasts (MEFs). PLOS ONE 9(5): e97316 PMID: 24845466 (#equal contributions; *corresponding authors)
  • Ningning Wu, Hongmei Zhang, Fang Deng, Ruidong Li, Wenwen Zhang, Xian Chen, Sheng Wen, Ning Wang, Junhui Zhang, Liangjun Yin, Zhan Liao, Zhonglin Zhang, Qian Zhang, Zhengjian Yan, Wei Liu, Di Wu, Jixing Ye, Youlin Deng, Ke Yang, Hue H. Luu, Rex C. Haydon, and Tong-Chuan He (2014) Overexpression of Ad5 Precursor Terminal Protein (pTP) Accelerates Recombinant Adenovirus Packaging and Amplification in HEK-293 Packaging Cells. Gene Therapy 21(7): 629-637, PMID: 24784448
  • Sheng Wen, Hongmei Zhang, Yasha Li, Ning Wang, Wenwen Zhang, Ke Yang, Ningning Wu, Xian Chen, Fang Deng, Zhan Liao, Junhui Zhang, Qian Zhang, Zhengjian Yan, Wei Liu, Zhonglin Zhang, Jixing Ye, Youlin Deng, Guolin Zhou, Hue H. Luu, Rex C. Haydon, Lewis L. Shi, Tong-Chuan He*, and Guanghui Wei* (2014) Characterization of Constitutive Promoters for piggyBac Transposon-mediated Stable Transgene Expression in Mesenchymal Stem Cells (MSCs). PLOS ONE 9(4): e94397. PMID: 24714676; PMCID: PMC3979777 (*Corresponding authors)
  • Ruidong Li, Wenwen Zhang, Jing Cui, Wei Shui, Liangjun Yin1, Yang Wang, Hongyu Zhang, Ning Wang, Ningning Wu, Guoxin Nan, Xian Chen, Sheng Wen, Fang Deng, Hongmei Zhang, Guolin Zhou, Zhan Liao, Junhui Zhang, Qian Zhang, Zhengjian Yan, Wei Liu, Zhonglin Zhang, Jixing Ye, Youlin Den, Hue H. Luu, Rex C. Haydon, Tong-Chuan He* and Zhong-Liang Deng* (2014)Targeting BMP9-Promoted Human Osteosarcoma Growth by Inactivation of Notch Signaling. Current Cancer Drug Targets 14: 274-285; PMID: 24605944 (*corresponding authors) [Featured as the Editor's Choice of the Issue]
  • Ning Wang, Hongyu Zhang, Bing-Qiang Zhang, Wei Liu, Zhonglin Zhang, Min Qiao, Hongmei Zhang, Fang Deng, Ningning Wu, Xian Chen, Sheng Wen, Junhui Zhang, Zhan Liao, Qian Zhang, Zhengjian Yan, Liangjun Yin, Jixing Ye, Youlin Deng, Hue H. Luu, Rex C. Haydon, Houjie Liang*, and Tong-Chuan He* (2014) Adenovirus-Mediated Efficient Gene Transfer into Cultured Three-Dimensional Organoids. PLOS ONE 9(4):e93608, PMID: 24695466 (*corresponding authors)
  • Jinhua Wang, Hongmei Zhang, Wenwen Zhang, Enyi Huang, Ning Wang, Ningning Wu, Sheng Wen, Xian Chen, Zhan Liao, Fang Deng, Liangjun Yin, Junhui Zhang, Qian Zhang, Zhengjian Yan, Wei Liu, Zhonglin Zhang, Jixing Ye, Youlin Deng, Hue H. Luu, Rex C. Haydon, Tong-Chuan He* and Feng Deng* (2014) BMP9 Effectively Induces Osteo/Odontoblastic Differentiation of the Reversibly Immortalized Stem Cells of Dental Apical Papilla (SCAPs). Stem Cells and Development 23(12):1405-1416 PMID: 24517722 (*co-corresponding authors)
  • Chen Zhao, Ningning Wu, Fang Deng, Hongmei Zhang, Ning Wang, Wenwen Zhang, Xian Chen, Sheng Wen, Junhui Zhang, Liangjun Yin, Zhan Liao, Zhonglin Zhang, Qian Zhang, Zhengjian Yan, Wei Liu, Di Wu, Jixing Ye, Youlin Deng, Guolin Zhou, Hue H. Luu, Rex C. Haydon, Weike Si*, and Tong-Chuan He* (2014) Adenovirus-Mediated Gene Transfer in Mesenchymal Stem Cells Can be Significantly Enhanced by the Cationic Polymer Polybrene. PLOS ONE 9(3): e92908. (*corresponding authors)
  • Wei Shui, Wenwen Zhang, Liangjun Yin, Guoxin Nan, Zhan Liao, Hongmei Zhang, Ning Wang, Ningning Wu, Xian Chen, Sheng Wen, Yunfeng He, Fang Deng, Junhui Zhang, Hue H. Luu, Lewis L Shi, Zhenming Hu, Rex C. Haydon, James Mok, and Tong-Chuan He (2014) Characterization of scaffold carriers for BMP9-transduced osteoblastic progenitor cells in bone regeneration. Journal of Biomedical Materials Research: Part A 102(10):3429-3438 PMID: 24133046
  • Yanhong Gao*, Enyi Huang, Hongmei Zhang, Jinhua Wang, Ningning Wu, Xian Chen, Ning Wang, Sheng Wen, Guoxin Nan, Fang Deng, Zhan Liao, Di Wu, Bosi Zhang, Junhui Zhang, Rex C. Haydon, Hue H. Luu, Lewis L Shi, and Tong-Chuan He* (2013) Crosstalk between Wnt/β-Catenin and Estrogen Receptor Signaling Synergistically Promotes Osteogenic Differentiation of Mesenchymal Progenitor Cells. PLoS One 8(12): e82436 (*corresponding authors)
  • Wenwen Zhang, Hongyu Zhang, Ning Wang, Chen Zhao, Hongmei Zhang, Fang Deng, Ningning Wu, Yunfeng He, Xian Chen, Junhui Zhang, Sheng Wen, Zhan Liao, Qian Zhang, Zhonglin Zhang, Wei Liu, Zhengjian Yan, Hue H. Luu, Rex C. Haydon, Lan Zhou, and Tong-Chuan He (2013) Modulation of β-Catenin Signaling by the Inhibitors of MAP Kinase, Tyrosine Kinase, and PI3-Kinase Pathways. International Journal of Medical Sciences 10(13):1888-1898 PMID: 24324366
  • Xian Chen, Gaurav Luther, Wenwen Zhang, Guoxin Nan, Eric R. Wagner, Zhan Liao, Ningning Wu, Hongmei Zhang, Ning Wang, Sheng Wen, Yunfeng He, Fang Deng, Junhui Zhang, Di Wu, Bosi Zhang, Rex C. Haydon, Lan Zhou, Hue H. Luu, and Tong-Chuan He: (2013) The E-F hand calcium-binding protein S100A4 regulates the proliferation, survival and differentiation potential of human osteosarcoma cells. Cellular Physiology and Biochemistry 32(4):1083-96
  • Jiye Zhang, Yaguang Weng, Xing Liu, Jinhua Wang, Wenwen Zhang, Stephanie H Kim, Hongyu Zhang, Ruidong Li, Yuhan Kong, Xiang Chen, Wei Shui, Ning Wang, Chen Zhao, Ningning Wu, Yunfeng He, Guoxin Nan, Xian Chen, Sheng Wen, Hongmei Zhang, Fang Deng, Lihua Wan, Hue H. Luu, Rex C. Haydon, Lewis L. Shi, Tong-Chuan He* and Qiong Shi* (2013) Endoplasmic reticulum (ER) stress inducible factor cysteine-rich with EGF-like domains 2 (Creld2) is an important mediator of BMP9-regulated osteogenic differentiation of mesenchymal stem cells. PLOS One 8(9): e73086 (corresponding authors)
  • Yuhan Kong, Hongyu Zhang, Xian Chen, Wenwen Zhang, Chen Zhao, Ning Wang, Ningning Wu, Yunfeng He, Guoxin Nan, Hongmei Zhang, Sheng Wen, Fang Deng, Zhan Liao, Di Wu, Junhui Zhang, Xinyue Qin, Rex C. Haydon, Hue H. Luu, Tong-Chuan He, and Lan Zhou (2013) Destabilization of Heterologous Proteins Mediated by the GSK3β Phosphorylation Domain of the β-Catenin Protein. Cellular Physiology and Biochemistry 32(5):1187-1199
  • Maureen Beederman*, Joseph D. Lamplot *, Guoxin Nan, Jinhua Wang, Xing Liu, Liangjun Yin, Ruidong Li, Wei Shui, Hongyu Zhang, Stephanie H. Kim, Wenwen Zhang, Jiye Zhang, Yuhan Kong, Sahitya Denduluri, Mary Rose Rogers, Abdullah Pratt, Rex C Haydon, Hue H. Luu, Jovito Angeles, Lewis L. Shi, and Tong-Chuan He (2013) BMP Signaling in Mesenchymal Stem Cell Differentiation and Bone Formation. Journal of Biomedical Science and Engineering 2013, 6, 32-52 (* These authors contributed equally to the work)
  • Ning Hu, Changdong Wang, Xi Liang, Liangjun Yin, Xiaoji Luo, Bo Liu, Hongyu Zhang, Wei Shui, Guoxin Nan, Ning Wang, Ningning Wu, Xian Chen, Yunfeng He, Sheng Wen, Fang Deng, Hongmei Zhang, Zhan Liao, Hue H. Luu, Rex C. Haydon, Tong-Chuan He, and Wei Huang (2013) Inhibition of Histone Deacetylases Potentiates BMP9-Induced Osteogenic Signaling in Mouse Mesenchymal Stem Cells. Cellular Physiology and Biochemistry 32(2): 486-498
  • Yi Wang, Siqi Hong, Ming Li, Jiye Zhang, Yang Bi, Yun He, Xing Liu, Guoxin Nan, Yuxi Su, Gaohui Zhu, Ruidong Li, Wenwen Zhang, Jinhua Wang, Hongyu Zhang, Yuhan Kong, Wei Shui, Ningning Wu, Yunfeng He, Xian Chen, Hue H. Luu, Rex C. Haydon, Lewis L. Shi, Tong-Chuan He* and Jiaqiang Qin* (2013) Noggin Resistance Contributes to the Potent Osteogenic Capability of BMP9 in Mesenchymal Stem Cells. Journal of Orthopaedic Research 31(11): 1796-1803 PMID: 23861103 (*corresponding authors)
  • Xing Liu, Jiaqiang Qin, Qing Luo, Yang Bi, Gaohui Zhu, Wei Jiang, Stephanie H Kim, Mi Li, Yuxi Su, Guoxin Nan, Jing Cui, Wenwen Zhang, Ruidong Li, Xiang Chen, Yuhan Kong, Jiye Zhang, Jinhua Wang, Mary Rose Rogers, Hongyu Zhang, Wei Shui, Chen Zhao, Ning Wang, Xi Liang, Ningning Wu, Yunfeng He, Hue H. Luu, Rex C. Haydon, Lewis L. Shi, Tingyu Li, Tong-Chuan He* and Ming Li* (2013) Crosstalk between EGF and BMP9 signaling pathways regulates the osteogenic differentiation of mesenchymal stem cells. Journal of Cellular and Molecular Medicine 17(9):1160-1172 PMID: 23844832 (*corresponding authors)
  • Mi Li, Yuan Chen, Yang Bi, Wei Jiang, Qing Luo, Yun He, Yuxi Su, Xing Liu, Jing Cui, Wenwen Zhang, Ruidong Li, Yuhan Kong, Jiye Zhang, Jinhua Wang, Hongyu Zhang, Wei Shui, Ningning Wu, Jing Zhu, Jie Tian, Qi-Jian Yi, Hue H. Luu, Rex C. Haydon, Tong-Chuan He* and Gao-Hui Zhu* (2013) Establishment and characterization of the reversibly immortalized mouse fetal heart progenitors. International Journal of Medical Sciences 10(8): 1035-1046 PMID: 23801891 open access (*corresponding authors)
  • Gaurav A. Luther, Joseph Lamplot, Xiang Chen, Richard Rames, Eric R. Wagner, Xing Liu, Akash Paresh, Enyi Huang, Stephanie H. Kim, Jikun Shen, Rex C. Haydon, Tong-Chuan He and Hue H. Luu (2013) IGFBP5 Domains Exert Distinct Inhibitory Effects on the Tumorigenicity and Metastasis of Human Osteosarcoma. Cancer Letters 336(1):222-230 PMID: 23665505
  • Xiaojun Wang, Jing Cui, Bing-Qiang Zhang, Hongyu Zhang, Yang Bi, Quan Kang, Ning Wang, Ping Bie, Zhanyu Yang, Huaizhi Wang, Xiangde Liu, Rex C Haydon, Hue H Luu, Ni Tang, Jiahong Dong* and Tong-Chuan He* (2013) Decellularized liver scaffolds effectively support the proliferation and differentiation of mouse fetal hepatic progenitors. Journal of Biomedical Materials Research: Part A 102(4):1017-1025 PMID: 23625886 (*co-corresponding authors)
  • Jian-Li Gao, Gui-Yuan Lv, Bai-Cheng He, Bing-Qiang Zhang, Hongyu Zhang, Ning Wang, Chong-Zhi Wang, Wei Du, Chun-Su Yuan, and Tong-Chuan He (2013) Ginseng saponin metabolite 20(S)-protopanaxadiol (PPD) inhibits tumor growth of by targeting multiple cancer signaling pathways. Oncology Reports 30(1):292-298 PMID: 23633038
  • Wei Shui, Liangjun Yin, Jeffrey Luo, Ruidong Li, Wenwen Zhang, Jiye Zhang, Wei Huang, Ning Hu, Xi Liang, Zhong-Liang Deng, Zhenming Hu, Lewis Shi, Hue H. Luu, Rex C. Haydon, Tong-Chuan He* and Sherwin Ho* (2013) Characterization of Chondrocyte Scaffold Carriers for Cell-based Gene Therapy in Articular Cartilage Repair. Journal of Biomedical Materials Research: Part A 101(12):3542-3550 PMID: 23629940 (*corresponding authors)
  • Ning Hu, Dianming Jiang, Enyi Huang, Xing Liu, Ruidong Li, Xi Liang, Stephanie H Kim, Xiang Chen, Jian-Li Gao, Hongyu Zhang, Wenwen Zhang, Yu-Han Kong, Jiye Zhang, Jinhua Wang, Wei Shui, Xiaoji Luo, Bo Liu, Jing Cui, Mary Rose Rogers, Jikun Shen, Chen Zhao, Ning Wang, Ningning Wu, Hue H. Luu, Rex C. Haydon, Tong-Chuan He* and Wei Huang* (2013): BMP9-regulated angiogenic signaling plays an important role in the osteogenic differentiation of mesenchymal stem cells. Journal of Cell Science 126: 532–541 PMID: 23203800 (*corresponding authors)
  • Joseph D. Lamplot, Jiaqiang Qin, Guoxin Nan, Jinhua Wang, Xing Liu, Liangjun Yin, Justin Tomal, Ruidong Li, Wei Shui, Hongyu Zhang, Stephanie H. Kim, Wenwen Zhang, Jiye Zhang, Yuhan Kong, Sahitya Denduluri, Mary Rose Rogers, Abdullah Pratt, Rex C Haydon, Hue H. Luu, Jovito Angeles, Lewis L. Shi, and Tong-Chuan He (2013): BMP9 Signaling in Stem Cell Differentiation and Osteogenesis. American Journal of Stem Cells 2(1): 1-21 PMID: 23671813
  • Joseph D. Lamplot, Sahitya Denduluri Jiaqiang Qin, Ruidong Li, Xing Liu, Hongyu Zhang, Xiang Chen, Ning Wang, Abdullah Pratt, Wei Shui, Xiaoji Luo, Guoxin Nan, Zhong-Liang Deng, Jinyong Luo, Rex C Haydon, Tong-Chuan He*, and Hue H. Luu* (2013): The Current and Future Therapies for Human Osteosarcoma. Current Cancer Therapy Reviews 9: 55-77 (*co-corresponding authors)
  • Kristofer E. Chenard, Chad M. Teven, Tong-Chuan He, and Russell R. Reid (2012) Bone Morphogenetic Proteins in Craniofacial Surgery: Current Techniques, Clinical Experiences, and the Future of Personalized Stem Cell Therapy. Journal of Biomedicine and Biotechnology, 2012:601549, PMID: 23226941
  • Jeong Hwan Kim, Xing Liu, Jinhua Wang, Xiang Chen, Hongyu Zhang, Stephanie H. Kim, Jing Cui, Ruidong L, Wenwen Zhang, Yuhan Kong, Jiye Zhang, Wei Shui, Joseph Lamplot, Mary Rose Rogers, Chen Zhao, Ning Wang, Prashant Rajan, Justin Tomal, Joseph Statz, Ningning Wu, Hue H. Luu, Rex C. Haydon, and Tong-Chuan He (2013): Wnt Signaling in Bone Formation and Its Therapeutic Potential for Bone Diseases. Therapeutic Advances in Musculoskeletal Disease 5(1):13-31
  • Matthew R. Greives, Eric A. Odessey, Darrel J. Waggoner, MD, Deana S. Shenaq, Swaroop Aradhya, Allison Mitchell, Neil Warshawsky, Tong-Chuan He and Russell R. Reid (2012) RUNX2 Quadruplication: additional Evidence Toward a New Form of Syndromic Craniosynostosis. Journal of Craniofacial Surgery 24(1): 126-129, PMID: 23348268
  • Rui-Dong Li, Zhong-Liang Deng, Ning Hu, Xi Liang, Bo Liu, Jinyong Luo, Liang Chen, Liangjun Yin, Xiaoji Luo, Wei Shui, Tong-Chuan He* and Wei Huang* (2012) Biphasic effects of TGFb1 on BMP9-induced osteogenic differentiation of mesenchymal stem cells. BMB Reports 45(9): 509-514 (*corresponding authors)
  • Enyi Huang, Gaohui Zhu, Wei Jiang, Ke Yang, Yanhong Gao, Qing Luo, Jian-Li Gao, Stephanie H Kim, Xing Liu, Mi Li, Qiong Shi, Ning Hu, Linyuan Wang, Hong Liu, Jing Cui, Wenwen Zhang, Ruidong Li, Xiang Chen, Yu-Han Kong, Jiye Zhang, Jinhua Wang, Jikun Shen, Yang Bi, Joseph Statz, Bai-Cheng He, Jinyong Luo, Huicong Wang, Feng Xiong, Hue H. Luu, Rex C. Haydon, Li Yang* and Tong-Chuan He* (2012) Growth hormone synergizes with BMP9 in osteogenic differentiation by activating the JAK/STAT/IGF1 pathway in murine multilineage cells. Journal of Bone and Mineral Research 27(7):1566-1575 (* corresponding authors)
  • Ke Yang, Jin Chen, Wei Jiang, Enyi Huang, Jing Cui, Stephanie H Kim, Ning Hu, Hong Liu, Wenwen Zhang, Ruidong Li, Xiang Chen, Yuhan Kong, Jiye Zhang, Jinhua Wang, Linyuan Wang, Jikun Shen, Hue H. Luu, Rex C. Haydon, Xiaohua Lian, Tian Yang* and Tong-Chuan He* (2012) Conditional Immortalization Establishes a Repertoire of Mouse Melanocyte Progenitors with Distinct Melanogenic Differentiation Potential. Journal of Investigative Dermatology 132(10): 2479-2483 (* corresponding authors)
  • Enyi Huang, Yang Bi, Wei Jiang, Xiaoji Luo, Ke Yang, Jian-Li Gao, Yanhong Gao, Qing Luo, Qiong Shi, Stephanie H Kim, Xing Liu, Mi Li, Ning Hu, Hong Liu, Jing Cui, Wenwen Zhang, Ruidong Li, Xiang Chen, Jikun Shen, Yuhan Kong, Jiye Zhang, Jinhua Wang, Jinyong Luo, Bai-Cheng He, Huicong Wang, Russell R. Reid, Hue H. Luu, Rex C. Haydon, Li Yang, and Tong-Chuan He (2012) Conditionally Immortalized Mouse Embryonic Fibroblasts Retain Proliferative Activity without Compromising Multipotent Differentiation Potential. PLoS ONE 7(2): e32428
  • Teven CM, Greives M, Natale R, Su Y, Luo Q, He BC, Shenaq D, He TC, Reid RR (2012) Differentiation of osteoprogenitor cells is induced by high-frequency pulsed electromagnetic fields. Journal of Craniofacial Surgery 23(2):586-593
  • Gaurav Luther, Eric R. Wagner, Gaohui Zhu, Quan Kang, Qing Luo, Joseph Lamplot, Yang Bi, Xiaoji Luo, Jinyong Luo, Chad Teven, Qiong Shi, Stephanie H. Kim, Jian-Li Gao, Enyi Huang, Ke Yang, Richard Rames, Xing Liu, Mi Li, Ning Hu, Hong Liu, Yuxi Su, Liang Chen, Bai-Cheng He, Guo-Wei Zuo, Zhong-Liang Deng, Russell R. Reid, Hue H. Luu, Rex C. Haydon, and Tong-Chuan He (2011) BMP-9 Induced Osteogenic Differentiation of Mesenchymal Stem Cells: Molecular Mechanism and Therapeutic Potential. Current Gene Therapy 11(3):229-240 PMID: 21453282
  • Chad M. Teven, Xing Liu, Ning Hu, Ni Tang, Stephanie H. Kim, Enyi Huang, Ke Yang, Mi Li, Jian-Li Gao, Hong Liu, Ryan B. Natale, Gaurav Luther, Qing Luo, Linyuan Wang, Richard Rames, Yang Bi, Jinyong Luo, Hue H Luu, Rex C Haydon, Russell R Reid and Tong-Chuan He (2011) Epigenetic Regulation of Mesenchymal Stem Cells: A Focus on Osteogenic and Adipogenic Differentiation. Stem Cells International 2011:201371, PMID: 21772852
  • Yuxi Su*, Eric R. Wagner*, Qing Luo, Jiayi Huang, Liang Chen, Bai-Cheng He, Guo-Wei Zuo, Qiong Shi, Bing-Qiang Zhang, Gaohui Zhu, Yang Bi, Jinyong Luo, Xiaoji Luo, Stephanie H. Kim, Jikun Shen, Farbod Rastegar, Enyi Huang, Yanhong Gao, Jian-Li Gao, Ke Yang, Christian Wietholt, Ming Li, Jiaqiang Qin, Rex C. Haydon, Tong-Chuan He, and Hue H. Luu (2011) Insulin-like Growth Factor Binding Protein 5 Suppresses Tumor Growth and Metastasis of Human Osteosarcoma. Oncogene 30(37):3907-3917 PMID: 21460855 (*equal contributions)
  • Bai-Cheng He*, Jian-Li Gao*, Bing-Qiang Zhang, Qing Luo, Qiong Shi, Stephanie H. Kim, Enyi Huang, Yanhong Gao, Ke Yang, Eric R. Wagner, Linyuan Wang, Ni Tang, Jinyong Luo, Xing Liu, Mi Li, Yang Bi, Jikun Shen, Gaurav Luther, Ning Hu, Qixin Zhou, Hue H. Luu, Rex C. Haydon, Yingming Zhao, and Tong-Chuan He (2011) Tetrandrine Inhibits Wnt/b-Catenin Signaling and Suppresses Tumor Growth of Human Colorectal Cancer. Molecular Pharmacology 79(2):211-219 PMID: 20978119 (*equal contributions)
  • Gaurav Luther, Richard Rames, Eric R. Wagner, Gaohui Zhu, Qing Luo, Yang Bi, Stephanie H. Kim, Jian-Li Gao, Enyi Huang, Ke Yang, Linyuan Wang, Xing Liu, Mi Li, Ning Hu, Yuxi Su, Xiaoji Luo, Liang Chen, Jinyong Luo,Rex C. Haydon, Hue H. Luu, Lan Zhou#, and Tong-Chuan He# (2010): Molecular Basis of Differentiation Therapy for Soft Tissue Sarcomas. Trends in Cancer Research 6:69-90 (#co-corresponding authors)
  • Eric R. Wagner*, Gaurav Luther*, Gaohui Zhu, Qing Luo, Qiong Shi, Stephanie H. Kim, Jian-Li Gao, Enyi Huang, Yanhong Gao, Ke Yang, Linyuan Wang, Chad Teven, Xiaoji Luo, Xing Liu, Mi Li, Ning Hu, Yuxi Su, Yang Bi, Bai-Cheng He, Ni Tang, Jinyong Luo, Liang Chen, Guowei Zuo, Richard Rames, Rex C. Haydon, Hue H. Luu#, and Tong-Chuan He# (2011) Defective Osteogenic Differentiation in the Development of Osteosarcoma. Sarcoma 2011:325238 PMID: 21437219 [PDF] (*equal contributions; #corresponding authors)
  • Justine C. Lee*, Lisa Spiguel*, Deana S. Shenaq, Ming Zhong, Christian Wietholt, Tong-Chuan He, and Russell R. Reid: (2011) The Role of RANK-RANKL-OPG Axis in Cranial Suture Homeostasis. Journal of Craniofacial Surgery 22(2): 699-705, PMID: 21415639 [*These authors contributed equally to the work]
  • Bai-Cheng He*, Jian-Li Gao*, Xiaoji Luo, Jinyong Luo, Jikun Shen, Linyuan Wang, Qixin Zhou, Yi-Tao Wang, Hue H. Luu, Rex C. Haydon, Chong-Zhi Wang, Wei Du, Chun-Su Yuan, Tong-Chuan He# and Bing-Qiang Zhang# (2011) Ginsenoside Rg3 inhibits colorectal tumor growth through the down-regulation of Wnt/b-catenin signaling. International Journal of Oncology 38: 437-445, PMID: 21152855 (*equal contributions; #co-corresponding authors)
  • Eric R. Wagner, Gaohui Zhu, Bing-Qiang Zhang, Qing Luo, Qiong Shi, Enyi Huang, Yanhong Gao, Jian-Li Gao, Stephanie H. Kim, Farbod Rastegar, Ke Yang, Bai-Cheng He, Liang Chen, Guo-Wei Zuo, Yang Bi, Yuxi Su, Jinyong Luo, Xiaoji Luo, Jiayi Huang, Zhong-Liang Deng, Russell R. Reid, Hue H. Luu, Rex C. Haydon, and Tong-Chuan He (2011) Therapeutic Potential of the Wnt Signaling Pathway in Bone Metabolic Disorders. Current Molecular Pharmacology 4(1): 14-25 PMID: 20825362
2000 ~ 2010
  • Jinyong Luo, Min Tang, Jiayi Huang, Bai-Cheng He, Jian-Li Gao, Liang Chen, Guo-Wei Zuo, Wenli Zhang, Qing Luo, Qiong Shi, Bing-Qiang Zhang, Yang Bi, Xiaoji Luo, Wei Jiang, Yuxi Su, Jikun Shen, Stephanie H. Kim, Enyi Huang, Yanhong Gao, Jian-Zhong Zhou, Ke Yang, Hue H. Luu, Xiaochuan Pan, Rex C. Haydon, Zhong-Liang Deng, and Tong-Chuan He (2010) TGFb/BMP Type I Receptors ALK1 and ALK2 Are Essential for BMP9-Induced Osteogenic Signaling in Mesenchymal Stem Cells. Journal of Biological Chemistry 285(38): 29588–29598 PMID: 20628059
  • Farbod Rastegar, Jian-Li Gao, Deana Shenaq, Qing Luo, Qiong Shi, Stephanie H. Kim, Wei Jiang, Eric R. Wagner, Enyi Huang, Yanhong Gao, Jikun Shen, Ke Yang, Bai-Cheng He, Liang Chen, Guo-Wei Zuo, Jinyong Luo, Xiaoji Luo, Yang Bi, Xing Liu, Mi Li, Ning Hu, Linyuan Wang, Gaurav Luther, Hue H. Luu, Rex C. Haydon, and Tong-Chuan He (2010) Lysophosphatidic acid acyltransferase b (LPAATb) promotes tumor growth of human osteosarcoma. PLoS ONE 5(12): e14182. doi:10.1371/journal.pone.0014182, PMID: 21152068
  • Deana S. Shenaq, Farbod Rastegar, Djuro Petkovic, Bing-Qiang Zhang, Bai-Cheng He, Liang Chen, Guo-Wei Zuo, Qing Luo, Qiong Shi, Eric R. Wagner, Enyi Huang, Yanhong Gao, Jian-Li Gao, Stephanie H. Kim, Ke Yang, Yang Bi, Yuxi Su, Gaohui Zhu, Jinyong Luo, Xiaoji Luo, Jiaqiang Qin, Russell R. Reid, Hue H. Luu, Rex C. Haydon and Tong-Chuan He (2010) Mesenchymal Progenitor Cells and Their Orthopedic Applications: Forging a Path towards Clinical Trials. Stem Cells International 2010: 519028 PMID: 21234334
  • Farbod Rastegar, Deana Shenaq, Jiayi Huang, Wenli Zhang, Bing-Qiang Zhang, Bai-Cheng He, Liang Chen, Guo-Wei Zuo, Qing Luo, Qiong Shi, Eric R. Wagner, Enyi Huang, Yanhong Gao, Jian-Li Gao, Stephanie H. Kim, Jian-Zhong Zhou, Yang Bi, Yuxi Su, Gaohui Zhu, Jinyong Luo, Xiaoji Luo, Jiaqiang Qin, Russell R. Reid, Hue H. Luu, Rex C. Haydon, Zhong-Liang Deng, Tong-Chuan He (2010) Mesenchymal Stem Cells: Molecular characteristics and clinical applications. World Journal of Stem Cells 2 (4): 67-80
  • Wenli Zhang, Zhong-Liang Deng, Liang Chen, Guo-Wei Zuo, Qing Luo, Qiong Shi, Bing-Qiang Zhang, Eric R. Wagner, Farbod Rastegar, Stephanie H. Kim, Wei Jiang, Jikun Shen, Enyi Huang, Yanhong Gao, Jian-Li Gao, Jian-Zhong Zhou, Jinyong Luo, Jiayi Huang, Xiaoji Luo, Yang Bi, Yuxi Su, Ke Yang, Hao Liu, Hue H. Luu, Rex C. Haydon, Tong-Chuan He*, and Bai-Cheng He* (2010) Retinoic Acids Potentiate BMP9-Induced Osteogenic Differentiation of Mesenchymal Progenitor Cells. PLoS ONE 5(7): e11917 (*co-corresponding authors)
  • Liang Chen, Wei Jiang, Jiayi Huang, Bai-Cheng He, Guo-Wei Zuo, Wenli Zhang, Qing Luo, Qiong Shi, Bing-Qiang Zhang, Eric R. Wagner, Jinyong Luo, Min Tang, Christian Wietholt, Xiaoji Luo, Yang Bi, Yuxi Su, Bo Liu, Stephanie H. Kim, Connie J. He, Yawen Hu, Jikun Shen, Farbod Rastegar, Enyi Huang, Yanhong Gao, Jian-Li Gao, Jian-Zhong Zhou, Russell R. Reid, Hue H. Luu, Rex C. Haydon, Tong-Chuan He*, and Zhong-Liang Deng* (2010) Insulin-like Growth Factor 2 (IGF2) Potentiates BMP9-induced Osteogenic Differentiation of Mesenchymal Stem Cells and Bone Formation. Journal of Bone and Mineral Research 25(11): 2447-2459 PMID: 20499340 (*co-corresponding authors) [Featured by Faculty of 1000, 06 Dec 2010; F1000.com/6670956]
  • Bai-Cheng He, Liang Chen, Guo-Wei Zuo, Wenli Zhang, Yang Bi, Jiayi Huang, Yi Wang, Wei Jiang, Qing Luo, Qiong Shi, Bing-Qiang Zhang, Bo Liu, Xia Lei, Jinyong Luo, Xiaoji Luo, Eric Wagner, Stephanie H. Kim, Connie J. He, Yawen Hu, Jikun Shen, Qixin Zhou, Farbod Rastegar, Zhong-Liang Deng, Hue H. Luu, Tong-Chuan He*, and Rex C. Haydon* (2010) Synergistic anti-tumor effect of the activated PPARg and retinoid receptors on human osteosarcoma. Clinical Cancer Research 16(8); 2235–2245 (*co-corresponding authors)
  • Eric Wagner, Bai-Cheng He, Liang Chen, Guo-Wei Zuo, Wenli Zhang, Qiong Shi, Qing Luo, Xiaoji Luo, Bo Liu, Jinyong Luo, Farbod Rastegar, Connie J. He, Yawen Hu, Barrett Boody, Hue H. Luu, Tong-Chuan He*, Zhong-Liang Deng, and Rex C. Haydon* (2010) Therapeutic Implications of PPARg in Human Osteosarcoma. PPAR Research 2010:956427 (*co-corresponding authors)
  • Guo-Wei Zuo, Christopher D. Kohls, Bai-Cheng He, Liang Chen, Wenli Zhang, Qiong Shi, Bing-Qiang Zhang, Quan Kang, Jinyong Luo, Xiaoji Luo, Eric R. Wagner, Stephanie H. Kim, Farbod Restegar, Rex C. Haydon, Zhong-Liang Deng, Hue H. Luu, Tong-Chuan He*, and Qing Luo* (2010) The CCN proteins: important signaling mediators in stem cell differentiation and tumorigenesis. Histology and Histopathology 25: 795-806 (*co-corresponding authors)
  • Jiayi Huang#, Yang Bi#, Gao-Hui Zhu, Yun He, Yuxi Su, Bai-Cheng He, Yi Wang, Quan Kang, Liang Chen, Guo-Wei Zuo, Qing Luo, Qiong Shi, Bing-Qiang Zhang, Ailong Huang, Lan Zhou, Tao Feng, Hue H. Luu, Rex C. Haydon, Tong-Chuan He, and Ni Tang (2009) Retinoic acid signaling induces the differentiation of mouse fetal liver-derived hepatic progenitor cells. Liver International 29(10): 1569-1581 (# These authors contributed equally to the work)
  • Gao-Hui Zhu, Jiayi Huang, Yang Bi, Yuxi Su, Yi Tang , Bai-Cheng He, Yun He, Jinyong Luo, Yi Wang, Liang Chen, Guo-Wei Zuo, Wei Jiang, Qing Luo, Jikun Shen, Bo Liu, Wen-Li Zhang, Qiong Shi, Bing-Qiang Zhang, Quan Kang, Jing Zhu, Jie Tian, Hue H. Luu, Rex C. Haydon, Yuan Chen, and Tong-Chuan He: (2009) Activation of RXR and RAR signaling promotes myogenic differentiation of myoblastic C2C12 cells. Differentiation 78: 195–204
  • Yang Bi#, Jiayi Huang#, Yun He, Gao-Hui Zhu, Yuxi Su, Bai-Cheng He, Jinyong Luo, Yi Wang, Quan Kang, Qing Luo, Liang Chen, Guo-Wei Zuo, Wei Jiang, Bo Liu, Qiong Shi, Min Tang, Bing-Qiang Zhang, Yaguang Weng, Ailong Huang, Lan Zhou, Tao Feng, Hue H. Luu, Rex C. Haydon, Tong-Chuan He,* and Ni Tang* (2009) Wnt Antagonist SFRP3 Inhibits the Differentiation of Mouse Hepatic Progenitor Cells. Journal of Cellular Biochemistry 108(1):295-303 (# These authors contributed equally to the work; *corresponding authors)
  • Yuxi Su, Xiaoji Luo, Bai-Cheng He, Yi Wang, Liang Chen, Guo-Wei Zuo, Bo Liu, Yang Bi, Jiayi Huang, Gao-Hui Zhu, Yun He, Quan Kang, Jinyong Luo, Jikun Shen, Jin Chen, Xianqing Jing, Rex C. Haydon, Tong-Chuan He, and Hue H. Luu: (2009) Establishment and characterization of a new highly metastatic human osteosarcoma cell line. Clinical & Experimental Metastasis 26:599–610
  • Ni Tang, Wen-Xin Song, Jinyong Luo, Xiaoji Luo, Jin Chen, Katie A.Sharff, Yang Bi, Bai-Cheng He, Jia-Yi Huang, Gao-Hui Zhu, Yu-Xi Su, Wei Jiang, Min Tang, Yun He, Yi Wang, Liang Chen, Guo-Wei Zuo, Jikun Shen, Xiaochuan Pan, Russell R. Reid, Hue H. Luu, Rex C. Haydon, and Tong-Chuan He: (2009) BMP9-induced osteogenic differentiation of mesenchymal progenitors requires functional canonical Wnt/b-catenin signaling. Journal of Cellular and Molecular Medicine 13 (8B):2448-2464
  • Katie A. Sharff*, Wen-Xin Song*, Xiaoji Luo, Ni Tang, Jinyong Luo, Jin Chen, Yang Bi, Bai-Cheng He, Jiayi Huang, Xinmin Li, Wei Jiang, Gao-Hui Zhu, Yuxi Su, Yun He, Jikun Shen, Yi Wang, Liang Chen, Guo-Wei Zuo, Bo Liu, Xiaochuan Pan, Russell R. Reid, Hue H. Luu, Rex C. Haydon#, and Tong-Chuan He#: (2009) Hey1 Basic Helix-Loop-Helix (bHLH) Protein Plays an Important Role in Mediating BMP9 Induced Osteogenic Differentiation of Mesenchymal Progenitor Cells. Journal of Biological Chemistry 284(1):649-659. (*equal contributions; # co-corresponding authors).
  • Quan Kang*, Wen-Xin Song*, Qing Luo, Ni Tang, Jinyong Luo, Xiaoji Luo, Jin Chen, Yang Bi, Bai-Cheng He, Jong Kyung Park, Wei Jiang, Yi Tang, Jiayi Huang, Yuxi Su, Gao-Hui Zhu, Yun He, Hong Yin, Zhenming Hu, Yi Wang, Liang Chen, Guowei Zuo, Xiaochuan Pan, Jikun Shen, Tamara Vokes, Russell Reid, Rex C. Haydon, Hue H. Luu#, and Tong-Chuan He#: (2009) A Comprehensive Analysis of the Dual Roles of BMPs in Regulating Adipogenic and Osteogenic Differentiation of Mesenchymal Progenitor Cells. Stem Cells and Development 18(4): 545-559 [PDF] (*equal contributions to the work; #co-corresponding authors)
  • Xiaoji Luo*, Jin Chen*, Wen-Xin Song, Ni Tang, Jinyong Luo, Zhong-Liang Deng, Katie A. Sharff, Gary He, Yang Bi, Bai-Cheng He, Erwin Bennett, Jiayi Huang, Quan Kang, Wei Jiang, Yuxi Su, Gao-Hui Zhu, Hong Yin, Yun He, Yi Wang, Jeffrey S. Souris, Liang Chen, Guo-Wei Zuo, Anthony G. Montag, Russell Reid, Rex C. Haydon, Hue H. Luu,# and Tong-Chuan He#: (2008) Osteogenic BMPs promote tumor growth of human osteosarcomas that harbor differentiation defects. Laboratory Investigation 88(12):1264-1277. (*equal contributions; # co-corresponding authors)
  • Xiaoji Luo, Katie A Sharff, Jin Chen, Tong-Chuan He and Hue H. Luu: (2008) S100A6 Expression and Function in Human Osteosarcoma. Clinical Orthopaedics and Related Research 466: 2060–2070
  • Chong-Zhi Wang, Han H. Aung, Bin Zhang, Shi Sun, Xiao-Li Li, Hui He, Jing-Tian Xie, Tong-Chuan He, Wei Du And Chun-Su Yuan: (2008) Chemopreventive Effects of Heat-processed Panax Quinquefolius Root on Human Breast Cancer Cells. Anticancer Research 28: 2545-51
  • Ni Tang, Wen-Xin Song, Jinyong Luo, Rex C. Haydon and Tong-Chuan He: (2008) Osteosarcoma Development and Stem Cell Differentiation. Clinical Orthopaedics and Related Research 466: 2114–2130
  • Xiaoji Luo, Chong-Zhi Wang, Jin Chen, Wen-Xin Song, Jinyong Luo, Ni Tang, Bai-Cheng He, Quan Kang, Yitao Wang, Wei Du, Tong-Chuan He*, and Chun-Su Yuan* (2008) Characterization of gene expression regulated by American ginseng and ginsenoside Rg3 in human colorectal cancer cells. International Journal of Oncology 32: 975-983. (*co-corresponding authors).
  • Zhong-Liang Deng, Katie A. Sharff, Ni Tang, Wen-Xin Song, Jinyong Luo, Xiaoji Luo, Jin Chen, Erwin Bennett, Russell Reid, David Manning, Anita Xue, Anthony G. Montag, Hue H. Luu, Rex C. Haydon and Tong-Chuan He: (2008) Regulation of osteogenic differentiation during skeletal development. Frontiers in Bioscience 13: 2001-2021.
  • Jinyong Luo, Zhong-Liang Deng, Xiaoji Luo, Ni Tang, Wen-Xin Song, Jin Chen, Katie A. Sharff, Hue H. Luu, Rex C. Haydon, Kenneth W. Kinzler, Bert Vogelstein, and Tong-Chuan He: (2007) A protocol for rapid generation of recombinant adenoviruses using the AdEasy system. Nature Protocols 2(5): 1236-1247
  • Qing Luo, Quan Kang, Wen-Xin Song, Hue H. Luu, Xiaoji Luo, Naili An, Jinyong Luo, Zhong-Liang Deng, Wei Jiang, Hong Yin, Jin Chen, Katie Sharff , Ni Tang, Erwin Bennett, Rex C. Haydon, and Tong-Chuan He: (2007) Selection and validation of optimal siRNA target sites for RNAi-mediated gene silencing. Gene 395(1-2): 160-169
  • Chong-Zhi Wang, Jing-Tian Xie, Bin Zhang, Ming Ni, Anna Fishbein, Han H. Aung, Sangeeta R. Mehendale, Wei Du, Tong-Chuan He, and Chun-Su Yuan: (2007) Chemopreventive effects of Panax notoginseng and its major constituents on SW480 human colorectal cancer cells. International Journal of Oncology 31(5):1149-1156
  • Patrick Bolt, Neil Clerk, Hue H. Luu, Quan Kang, Jennifer L. Kummer, Zhong-Liang Deng, Kirstina Olson, Frank Primus, Anthony G. Montag, Tong-Chuan He, Rex C. Haydon, and Brian C. Toolan: (2007) BMP14 gene therapy increases tendon tensile strength in a rat model of Achilles tendon injury. Journal of Bone and Joint Surgery (American) 89:1315-1320
  • Hue H. Luu, Wen-Xin Song, Xiaoji Luo, David Manning, Jinyong Luo, Zhongliang Deng, Katie Sharff, Anthony G. Montag, Rex C. Haydon, and Tong-Chuan He: (2007) Distinct Roles of Bone Morphogenetic Proteins in Osteogenic Differentiation of Mesenchymal Stem Cells. Journal of Orthopaedic Research 25(5): 665-677.
  • Yu-Hua Tseng and Tong-Chuan He: (2007) Bone Morphogenetic Proteins and Adipocyte Differentiation. Cellscience Reviews 3(3): 342-360
  • Jinyong Luo, Jin Chen, Zhong-Liang Deng, Xiaoji Luo, Wen-Xin Song, Katie Sharff, Ni Tang, Rex C. Haydon, Hue H. Luu, and Tong-Chuan He: (2007) Wnt signaling and human diseases: what are the therapeutic implications? Laboratory Investigation 87(2): 97-103.
  • Rex C. Haydon, Hue H. Luu, and Tong-Chuan He: (2007) Osteosarcoma and Osteoblastic Differentiation: A New Perspective on Oncogenesis. Clinical Orthopaedics and Related Research 454: 237-246.
  • Chong-Zhi Wang, Bin Zhang, Wen-Xin Song, Anbao Wang, Ming Ni, Xiaoji Luo, Han H. Aung, Jing-Tian Xie, Robin Tong, Tong-Chuan He, and Chun-Su Yuan. (2006) Steamed American Ginseng Berry: Ginsenoside Analyses and Anticancer Activities. Journal of Agriculture and Food Chemistry 54: 9936-9942.
  • Zhang BQ, Huang Y, Tang N, Wu Y, Zhang J, Chen WX, He TC, Huang AL. (2006) Inhibition of HBV replication and antigen expression by RNA interference against different targets. Chinese Journal of Hepatology (Zhonghua Gan Zang Bing Za Zhi) 14 (9):662-5.
  • Wang CZ, Luo X, Zhang B, Song WX, Ni M, Mehendale S, Xie JT, Aung HH, He TC, Yuan CS. (2006) Notoginseng enhances anti-cancer effect of 5-fluorouracil on human colorectal cancer cells. Cancer Chemother Pharmacol. 2006 Sep 29; [Epub ahead of print].
  • Weike Si, Quan Kang, Hue H. Luu, Jong Kyung Park, Qing Luo, Wen-Xin Song, Wei Jiang, Xiaoji Luo, Xinmin Li, Hong Yin, Anthony G. Montag, Rex C. Haydon, and Tong-Chuan He: (2006) CCN1/Cyr61 is regulated by canonical Wnt signal and plays an important role in Wnt3A-induced early osteogenic differentiation. Molecular and Cellular Biology 26(8): 2955–2964.
  • Yejia Zhang, Howard S. An, Eugene J-M.A. Thonar, Susan Chubinskaya, Tong-Chuan He, and Frank M. Phillips. (2006) Comparative effects of bone morphogenetic proteins and sox9 overexpression on extracellular matrix metabolism of bovine nucleus pulposus cells. Spine 31(19): 2173-9.
  • Hue H. Luu, Quan Kang, Jong Kyung Park, Weike Si, Qing Luo, Wei Jiang, Hong Yin, Anthony G. Montag, Michael A. Simon, Terrance D. Peabody, Rex C. Haydon, Carrie W. Rinker-Schaeffer, and Tong-Chuan He: (2005) An orthotopic model of human osteosarcoma growth and spontaneous pulmonary metastasis. Clinical & Experimental Metastasis 22(4): 319-329.
  • Hue H. Luu, Lan Zhou, Rex C. Haydon, Andrea T. Deyrup, Anthony G. Montag, Dezheng Huo, Robert Heck, Claus W. Heizmann, Terrance Peabody, Michael A. Simon, and Tong-Chuan He: (2005) Increased expression of S100A6 is associated with decreased metastasis and inhibition of cell migration and anchorage independent growth in human osteosarcoma. Cancer Letters 229(1): 135-148.
  • Frank M. Phillips, Patrick Bolt, Tong-Chuan He, and Rex C. Haydon: (2005) Gene Therapy for Spinal Fusion. Spine Journal 5 (6 Suppl): S250-258.
  • T.-C. He: (2005) Distinct osteogenic activity of BMPs and their orthopaedic applications. Journal of Musculoskeletal & Neuronal Interactions 5(4): 363-366.
  • Yejia Zhang, Zhen Li, Eugene J-M.A. Thonar, Howard S. An, Tong-Chuan He, Daniel Pietryla, and Frank M. Phillips: (2005) Transduced bovine articular chondrocytes affect the metabolism of co-cultured nucleus pulposus cells in vitro: Implications for chondrocyte transplantation into the intervertebral disc. Spine 30(23): 2601-7.
  • Jun Sun, Michael E. Hobert, Yingli Duan, Anjali S. Rao, Tong-Chuan He, Eugene B. Chang, James L. Madara: (2005) Crosstalk between NF-kappaB and beta-catenin pathways in bacterial-colonized intestinal epithelial cells. American Journal of Physiology - Gastrointestinal and Liver Physiology 289(1): G129-37.
  • P. Tao, J. Zhang, N. Tang, B.-Q. Zhang, T.-C. He, and A.-L. Huang: (2005) Potent and specific inhibition of SARS-CoV antigen expression by RNA interference. Chinese Medical Journal (Engl.) 118(9):714-719.
  • Jeffrey Luo, Daniel P. Mass, Craig S. Phillips, and Tong-Chuan He: (2005) The Future of Flexor Tendon Surgery. Hand Clinic 21(2): 267-273.
  • Jeffrey Luo, Michael H. Sun, Quan Kang, Ying Peng, Wei Jiang, Hue H. Luu, Qing Luo, Jae Yoon Park, Yien Li, Rex C. Haydon, and Tong-Chuan He: (2005) Gene Therapy for Bone Regeneration. Current Gene Therapy 5(2): 167-179.
  • Olaronke Akintola-Ogunremi, Qing Luo, Tong-Chuan He, and Hanlin L. Wang: (2005) Is Cytomegalovirus Associated with Human Colorectal Tumorigenesis? American Journal of Clinical Pathology 123: 244-249.
  • Vishal Mehta, Quan Kang, Jeffrey Luo, Tong-Chuan He, Rex C. Haydon, and Daniel P. Mass: (2005) Characterization of Adenovirus-mediated Gene Transfer in Rabbit Flexor Tendons. Journal of Hand Surgery 30(1):136-141.
  • Qing Luo*, Quan Kang*, Weike Si, Wei Jiang, Jong Kyung Park, Ying Peng, Xinmin Li, Hue H. Luu, Jeffrey Luo, Anthony G. Montag, Rex C. Haydon, and Tong-Chuan He: (2004) Connective Tissue Growth Factor (CTGF) is regulated by Wnt and BMP signaling in osteoblast differentiation of mesenchymal stem cells. Journal of Biological Chemistry 279 (53): 55958-55968. (*contributed equally to this work)
  • Hue H. Luu, Ruiwen Zhang, Rex C. Haydon, Elizabeth Rayburn, Quan Kang, Weike Si, Jong Kyung Park, Hui Wang, Ying Peng, Wei Jiang, and Tong-Chuan He: (2004) Wnt/beta-Catenin Signaling Pathway as Novel Cancer Drug Targets. Current Cancer Drug Targets 4: 653-671.
  • Quan Kang*, Michael H. Sun*, Hongwei Cheng*, Ying Peng, Anthony G. Montag, Andrea T. Deyrup, Wei Jiang, Hue H. Luu, Jan Paul Szatkowski, Pantila Vanichakarn, Jae Yoon Park, Jeffrey Luo, Yien Li, Rex C. Haydon, and Tong-Chuan He: (2004) Characterization of the distinct orthotopic bone forming activity of 14 BMPs using recombinant adenovirus-mediated gene delivery. Gene Therapy 11 (17): 1312–1320. (*contributed equally to this work)
  • Ying Peng*, Quan Kang*, Qing Luo, Wei Jiang, Weike Si, Bernard A. Liu, Hue H. Luu, Jong Kyung Park, Xinmin Li, Jeffrey Luo, Anthony G. Montag, Rex C. Haydon, and Tong-Chuan He: (2004) Id Helix-Loop-Helix Proteins Mediate BMP-induced Osteoblast Differentiation of Mesenchymal Stem Cells. Journal of Biological Chemistry 279(31): 32941-32949. (*contributed equally to this work)
  • Rex C. Haydon, Lan Zhou, and Tong-Chuan He: (2004) Commentary: Tyrosine Kinase Inhibitor STI-571: The New Wonder Drug of Cancer Therapy? Cancer Biology and Therapy 3(4): 393-394.
  • Jae Yoon Park, Qing Luo, Wei Jiang, Quan Kang, Ying Peng, Catherine Strom, Hue H. Luu, Rex C. Haydon, and Tong-Chuan He: (2004) Dual Regulation of Gene Expression Mediated by Tetracycline and Cre Recombinase. BioTechniques 39(3): 390-396.
  • Ying Peng, Quan Kang, Hongwei Cheng, Xinmin Li, Michael H. Sun, Wei Jiang, Hue H. Luu, Jae Yoon Park, Rex C. Haydon, and Tong-Chuan He: (2003) Transcriptional Characterization of Bone Morphogenetic Proteins (BMPs)-Mediated Osteogenic Signaling. Journal of Cellular Biochemistry 90: 1149-1165.
  • N. Tang, A. L. Huang, B. Q. Zhang, G. Yan, and T.-C. He: (2003) Potent and specific inhibition of hepatitis B virus antigen expression by RNA interference. Chinese Medical Journal (Engl.) 83(15):1309-1312.
  • Andrea T. Deyrup, Rex C. Haydon, Dezheng Huo, Akira Ishikawa, Terrance D. Peabody, Tong-Chuan He, and Anthony G. Montag: (2003) Myoid Differentiation And Prognosis In Adult Pleomorphic Sarcomas Of The Extremity: An Analysis Of 93 Cases. Cancer 98 (4): 805-813.
  • Hongwei Cheng, Wei Jiang, Frank M. Phillips, Rex C. Haydon, Ying Peng, Lan Zhou, Hue H. Luu, Naili An, Benjamin Breyer, Pantila Vanichakarn, Jan Paul Szatkowski, Jae Yoon Park, and Tong-Chuan He: (2003) Osteogenic Activity of the 14 Types of Human Bone Morphogenetic Proteins (BMPs). Journal of Bone and Joint Surgery 85(8): 1544-1552.
  • M.Q. Xiang, A.L. Huang, N. Tang, Y.J. Xiao, G. Yan, and T.-C. He: (2003) The expression of Recombinant adenovirus IkappaBalphaM in human hepatocarcinoma HepG(2) and it's inhibitive effect to the activity of NF-kappaB. Chinese Medical Journal (Engl.) 83(13): 1156-1160.
  • Michael H. Sun, Hongwei Cheng, Frank Phillips, Rex C. Haydon, and Tong-Chuan He: (2003) BMPs and Bone Regeneration. Advances in Osteoporotic Fracture Management 2(3): 70-78.
  • Lan Zhou, Naili An, Rex C. Haydon, Qixin Zhou, Hongwei Cheng, Ying Peng, Wei Jiang, Pantila Vanichakarn, Jan Paul Szatkowski, Jae Yoon Park, Benjamin Breyer, and Tong-Chuan He: (2003) Tyrosine kinase inhibitor STI-571/Gleevec down-regulates the beta-catenin signaling activity. Cancer Letters 193(2): 161-170.
  • Ronjon Paul*, Rex C. Haydon*, Hongwei Cheng, Akira Ishikawa, Nikola Nenadovich, Wei Jiang, Lan Zhou, Benjamin Breyer, Tao Feng, Purnendu Gupta, Tong-Chuan He, and Frank Phillips: (2003) Potential use of Sox9 gene therapy for intervertebral degenerative disc diseases. Spine 28(8): 755-763. (*contributed equally to this work)
  • Lan Zhou, Naili An, Wei Jiang, Rex Haydon, Hongwei Cheng, Qixin Zhou, Benjamin Breyer, Tao Feng, and Tong-Chuan He: (2002) Fluorescence-based Functional Assay for the Wnt/beta-Catenin Signaling Activity. BioTechniques 33(5):1126-1135.
  • Rex C. Haydon, Andrea Deyrup, Akira Ishikawa, Robert Heck, Wei Jiang, Lan Zhou, Tao Feng, David King, Hongwei Cheng, Benjamin Breyer, Terrance Peabody, Michael Simon, Anthony Montag, and Tong-Chuan He: (2002) Cytoplasmic and/or Nuclear Accumulation of the beta-Catenin Protein is a Frequent Event in Human Osteosarcoma. International Journal of Cancer. 102(4):338-342.
  • Tong-Chuan He. Association of COX-2 and PPARs in Carcinogenesis and Chemoprevention. In COX-2 Blockade in Cancer Prevention and Therapy, Ed. R. E. Harris, Humana Press, Inc., New Jersey. pp225-244, 2002.
  • Hanlin L. Wang, Julia Wang, Shu-Yuan Xiao, Rex Haydon, Debra Stoiber, Tong-Chuan He, Marc Bissonnette, and John Hart. (2002) Elevated protein expression of cyclin D1 and Fra-1, but decreased expression of c-Myc, in human colorectal adenocarcinomas overexpressing beta-catenin. International Journal of Cancer 101:301-310.
  • Tao Feng, Zhenggong Li, Wei Jiang, Benjamin Breyer, Lan Zhou, Hongwei Cheng, Rex C. Haydon, Akira Ishikawa, Mohanad A. Joudeh, and Tong-Chuan He: (2002) Increased efficiency of cloning large DNA fragments using a lower copy number plasmid. BioTechniques 32(5): 992-998. Rex C. Haydon, Lan Zhou, Tao Feng, Benjamin Breyer, Hongwei Cheng, Wei Jiang, Terrance Peabody, Anthony Montag, Michael A. Simon, and Tong-Chuan He: (2002) Nuclear receptor agonists as potential differentiation therapy agents for human osteosarcoma. Clinical Cancer Research 8: 1288-1294.
  • Benjamin Breyer, Wei Jiang, Hongwei Cheng, Rex Haydon, Lan Zhou, Tao Feng, Akira Ishikawa, and Tong-Chuan He: (2002) Development and Use of Viral Vectors for Gene Transfer: Lessons from Their Applications in Gene Therapy. Applied Genomics and Proteomics. 1(1): 45-63.
  • Wei Jiang*, Lan Zhou*, Benjamin Breyer*, Tao Feng, Hongwei Cheng, Rex Haydon, Akira Ishikawa, and Tong-Chuan He: (2001) Tetracycline-regulated gene expression mediated by a novel chimeric repressor that recruits histone deacetylases in mammalian cells. Journal of Biological Chemistry 276 (48): 45168-45174. (*contributed equally to this work)
  • Tong-Chuan He. Unit 12.4: Adenoviral Vectors, in Current Protocols in Human Genetics John Wiley & Sons, Inc., New York, pp12.4.1-12.4.21, 2001.
  • Benjamin Breyer, Wei Jiang, Hongwei Cheng, Lan Zhou, Ronjon Paul, Tao Feng, and Tong-Chuan He: (2001) Adenoviral vector-mediated gene transfer for human gene therapy. Current Gene Therapy 1(2): 149-162.
  • Ben H. Park, Benjamin Breyer, and Tong-Chuan He: (2001) Peroxisome proliferation-activated receptors: roles in tumorigenesis and chemoprevention in human tumor. Current Opinion in Oncology 13:78-83.
Prior to 2000
  • Ie-Ming Shih, Jian Yu, Tong-Chuan He, Bert Vogelstein, and Kenneth W. Kinzler (2000) The beta-catenin binding domain of Adenomatous polyposis Coli is sufficient for tumor suppression. Cancer Research 60:1671-1676. [PDF]
  • Luis T. da Costa, Tong-Chuan He, Jian Yu, Andrew B. Sparks, Patrice J. Morin, Kornelia Polyak, Steve Laken, Bert Vogelstein, and Kenneth W. Kinzler: (1999) Cdx2 is mutated in a colorectal cancer with normal APC/beta-catenin signaling. Oncogene, 18:5010-5014. [PDF]
  • Tong-Chuan He, Timothy A. Chan, Bert Vogelstein, and Kenneth W. Kinzler: (1999) PPAR delta is an APC regulated target of nonsteroidal anti-inflammatory drugs. Cell 99:335-345. [PDF]
  • Tong-Chuan He, Andrew B. Sparks, Carlo Rago, Heiko Hermeking, Leigh Zawel, Luis T. da Costa, Patrice J. Morin, Bert Vogelstein, and Kenneth W. Kinzler: (1998) Identification of c-Myc as a target of the APC pathway. Science, 281:1509-1512. [PDF]
  • Tong-Chuan He, Shibin Zhou, Luis da Costa, Jian Yu, Kenneth W. Kinzler, and Bert Vogelstein: (1998) A simplified system for generating recombinant adenoviruses. Proceedings of National Academy of Sciences USA 95:2509-2514. [PDF]
  • Velculescu, V.E., Madden, S.L., Zhang, L., Lash, A.E., Yu, J., Rago, C., Lal, A., Wang, C.J., Ciriello, K.M., Cook, B.P., Dufault, M.R., Ferguson, A.T., Gao,Y., He, T.-C., Hermeking, H., Hiralo,S.K., Hwang, P.M., Lopez, M.A., Luderer, H.F., Mathews, B., Petroziello, J.M., Polyak, K., Zawel, L., Zhang, W., Zhang, X., Zhou, W., Haluska, F.G., Jen, J., Sukumar, S., Landes, G.M., Riggins, G.J., Vogelstein, B., and Kinzler, K.W. (1999) Analysis of human transcriptomes. Nature Genetics 23:387-388. [PDF]
  • Heiko Hermeking, Christoph Lengauer, Kornellia Polyak, Tong-Chuan He, Lin Zhang, Sam Thiagalingam, Kenneth W. Kinzler, and Bert Vogelstein: (1998) 14-3-3sigma is a p53-regulated inhibitor of G2/M progression. Molecular Cell 1:3-11.
  • Tong-Chuan He, Luis da Costa, and Sam Thiagalingam: (1997) Homeosis and polyposis: a tale from the mouse. BioEssays 19(7):551-555.
  • Kornelia Polyak, Todd Waldman, Tong-Chuan He, Kenneth W. Kinzler, and Bert Vogelstein: (1996) Genetic determinants of p53-induced apoptosis and growth arrest. Genes & Development 10:1945-1952.
  • Luis da Costa, Jin Jen, Tong-Chuan He, Timothy A Chan, Kenneth W Kinzler and Bert Vogelstein: (1996) Converting cancer genes into killer genes. Proceedings of National Academy of Sciences USA 93:4192-4196 [PDF]
  • Ning Jiang, Tong-Chuan He, Atsushi Miyajima, and Don M. Wojchowski: (1996) The box-1 domain of the EPO receptor specifies Jak2 and functions mitogenically within an IL2beta-receptor chimera. Journal of Biological Chemistry 271:16472-16476.
  • Tong-Chuan He, Ning Jiang, Hongming Zhuang, Don M. Wojchowski: (1995) Erythropoietin-induced recruitment of Shc via a receptor phosphotyrosine-independent, Jak2-dependent pathway. Journal of Biological Chemistry 270:11055-11061.
  • Hongming Zhuang, Zhutian Niu, Tong-Chuan He, Sunil V. Patel, Don M. Wojchowski: (1995) Erythropoietin-dependent inhibition of apoptosis is supported by carboxy-truncated receptor forms, and blocked by dominant negative forms of Jak2. Journal of Biological Chemistry 270:14500-14504.
  • Tong-Chuan He, Ning Jiang, Hongming Zhuang, Dawn E. Quelle, Don M.Wojchowski: (1994) The extended box-2 subdomain of erythropoietin receptor is nonessential for Jak2 activation yet critical for efficient mitogenesis in FDC-ER cells. Journal of Biological Chemistry 269:18291-18294.
  • Hongming Zhuang, Sunil V. Patel, Tong-Chuan He, Zhutian Niu, Don M. Wojchowski: (1994) Dominant negative effects of a carboxy-truncated Jak2 mutant on EPO-induced proliferation and Jak2 activation. Biochemical and Biophysical Research Communication 204(1):278-283.
  • Hongming Zhuang, Sunil V. Patel, Tong-Chuan He, Sherill K. Sonsteby, Zhutian Niu, Don M. Wojchowski: (1994) Inhibition of erythropoietin-induced mitogenesis by a kinase-deficient form of Jak2. Journal of Biological Chemistry 269:21411-21414.
  • Tong-Chuan He, Hongming Zhuang, Ning Jiang, Michael D. Waterfield, Don M. Wojchowski: (1993) Association of the p85 regulatory subunit of phosphatidylinositol 3-kinase with an essential erythropoietin receptor subdomain. Blood 82: 3530-3538.
  • Don M. Wojchowski and Tong-Chuan He: (1993) A concise review: Signal transduction in the erythropoietin receptor system. Stem Cells 11:381-392.
  • Qian Li, Tong-Chuan He, Zheng-Tai Wang: (1990) Establishment and comparison of three methods for GABA-transaminase activity measurement. Acta Universitatis Scientiae Medicinae Chongqing 15: 70.
  • Tong-Chuan He and Zheng-Tai Wang: (1989). Identification and characterization of a cerebral GABA-transaminase inhibitor in the livers from the acute liver failure mice. Acta Universitatis Scientiae Medicinae Chongqing 14: 172.
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